Cornell University Announcements Graduate School of Medical Sciences 1983-1984 1 Digitized by the Internet Archive in 2013 http://archive.org/details/comelluniversit1983corn Cornell University Graduate School of Medical Sciences 1300 York Avenue New York, New York 10021 Telephone 212/472-5670 1983-84 2 1983-1984 Calendar 1983 Registration for first trimester* and fall semester**; orientation for new students First trimester and fall semester begin Labor Day holiday First trimester ends Examinations for first trimester Thanksgiving recess Registration for second trimester* Instruction begins for second trimester Winter recess: Instruction suspended, 5:00 p.m. Monday, August 29, and Tuesday, August 30 Wednesday, August 31 Monday, September 5 Wednesday, November 16 Thursday, November 1 7-Wednesday, November 23 Thursday, November 24, and Friday, November 25 Wednesday, November 23, and Monday, November 28 Monday, November 28 Friday, December 16 1984 Winter recess: Instruction resumed, 9:00 a.m. Last day for completing requirements for January degrees Fall semester ends; conferral of January degrees Registration for spring semester** Spring semester begins Second trimester ends Washington's Birthday observed Examinations for second trimester Registration for third trimester Third trimester begins Spring recess: Instruction suspended, 5:00 p.m. Instruction resumed, 9:00 a.m. Last day for completing requirements for May degi Commencement Day; conferral of May degrees Third trimester and spring semester end Memorial Day holiday observed Examinations for third trimester Tuesday, January 3 Friday, January 6 Friday, January 20 Friday, January 20, and Monday, January 23 Monday, January 23 Friday, February 1 7 Monday, February 20 Tuesday, February 21 -Friday, March 2 Friday, March 2, and Monday, March 5 Monday, March 5 Friday, March 30 Monday, April 9 Friday, May 18 Tuesday, May 22 Friday, May 25 Monday, May 28 Tuesday, May 29-Friday, June 1 Summer Term Registration for summer research term Monday, June 4 Summer research term begins Monday, June 4 Last day for completing requirements for August degrees Friday, August 10 Summer research term ends; conferral of August degrees Friday, August 24 'for students enrolling in courses "for students conducting research only, who are on leave of absence, or are in absentia Note Courses are trimestral; degrees are granted at the ends of the fall and spring semesters and of the summer term The dates shown in the calendar are subject to change at any time by official action of Cornell University In enacting this calendar, the Graduate School of Medical Sciences has scheduled classes on religious holidays It is the intent of the school that students missing classes due to the observance of religious holidays be given ample opportunity to make up work 3 Announcement Contents 2 Calendar 5 Graduate School of Medical Sciences 5 Purpose and History 5 Facilities 5 Organization 6 Admission 7 Degree Requirements 9 Tuition and Fees 10 Financial Assistance 10 Scholarships and Awards 1 1 Student Health Services 11 Residence Halls 13 Fields of Instruction 13 Instruction at the Medical College Division 23 Instruction at the Sloan-Kettering Division 30 Interdivisional Course 30 Special Programs 32 Register 44 Aerial View of Buildings 43 Index 42 List of Announcements The courses and curricula described in this Announcement, and the teaching personnel listed herein, are as of July 1 , 1983 and are subject to change at any time by official action of Cornell University. 4 The New York Hospital — Cornell Medical Center 5 Cornell University Graduate School of Medical Sciences Purpose The Graduate School of Medical Sciences, a semi- autonomous component of the Graduate School of Cornell University, provides opportunities for advanced study and research training in specific areas of the biomedical sciences. Graduate programs leading to the degrees of Doctor of Philosophy are offered in the fields of biochemistry, biophysics, cell and develop- mental biology, developmental therapy, genetics, immunobiology, molecular biology, microbiology, neu- robiology and behavior, pathology, pharmacology, physiology, and virology Certain of these fields of study also offer programs leading to the degree of Master of Science. Collaborative programs with Cor- nell University Medical College lead to the combined degrees of Doctor of Philosophy and Doctor of Medicine. The faculty of the Graduate School of Medical Sci- ences recommends the award of advanced general degrees not only as the result of the fulfillment of certain formal academic requirements, but also as evidence of the development and possession of a critical and creative ability in science. Demonstration of this ability is embodied in a dissertation which the candidate presents to the faculty as an original re- search contribution in the chosen area of study. A close working relationship between student and fac- ulty is essential to the program of the Cornell University Graduate School of Medical Sciences. Guidance for each student is provided by a Special Committee, a group of at least three faculty members selected by the student. This Special Committee is granted extraordinary independence in working with its student. Other than a broad framework of Graduate School of Medical Sciences requirements for resi- dence, examinations, and a thesis, and additional requirements of the particular field of study chosen by the student, the Special Committee is free to design an individualized program of study with its student. No overall course, credit-hour, or grade requirements are set by the Graduate School of Medical Sciences. A student is recommended for a degree whenever the Special Committee judges the student qualified. History The opportunity for graduate study leading to ad- vanced general degrees in the biomedical sciences was first offered at the Cornell University Medical Col- lege, in cooperation with the Graduate School of Cornell University, in 1912. In June of 1950, Cornell University, in association with the Sloan-Kettering In- stitute for Cancer Research, established additional opportunities for graduate study by forming the Sloan- Kettering Division of the Medical College. The result- ing expansion of both graduate faculty and research training opportunities on the New York City campus prompted the organization in January 1952 of the Graduate School of Medical Sciences, composed of two cooperative but separate divisions, known as the Medical College Division and the Sloan-Kettering Divi- sion. The Graduate School of Medical Sciences was given full responsibility for advanced general degrees granted for study in residence at the New York City campus of Cornell University. Facilities Despite the divisional structure of the Graduate School of Medical Sciences, the courses offered by the two Divisions are open to all students, as are the general facilities of the Divisions such as libraries, dining halls, and recreational resources. The Medical College Division. The buildings along York Avenue between 68th and 70th Streets accom- modate both Cornell University Medical College and the Medical College Division of the Graduate School of Medical Sciences. Facilities available to graduate students include the Samuel J. Wood Library with a collection of over 123,000 volumes and subscriptions to 1,880 current journals, lecture rooms, study labora- tories, seminar rooms, and libraries of the basic science departments. Extensive research facilities are provided for faculty and students. The Sloan-Kettering Division. Its facilities are lo- cated within the Sloan-Kettering Institute for Cancer Research, which consists of the Howard, Kettering, and Schwartz Laboratory buildings on East 68th Street. In addition, the Walker Laboratory is located in Rye, New York. Each provide lecture and seminar rooms, and together represent more than 100 labora- tories, which are available for biomedical research training. The Lee Coombe Memorial Library with 28,000 volumes of books and journals is located in the 68th Street complex. Organization The faculty of the Graduate School of Medical Sci- ences is composed of the faculties of the Medical College Division, consisting primarily of the profes- sional staff of the basic sciences departments of Cornell University Medical College, and of the Sloan- Kettering Division, consisting of those professional 6 Admission staff members of the Sloan-Kettering Institute for Can- cer Research who hold faculty appointments. Within each of the Divisions are Fields (Medical Col- lege Division) and Units (Sloan-Kettering Division) of graduate instruction which are formed by the faculty members in the respective Divisions with similar re- search and teaching interests. These Fields and Units of the Graduate School of Medical Sciences represent areas of concentration in which advanced degrees are offered. Executive Committee The Executive Committee is both the administrative and judicial board of the Graduate School of Medical Sciences and its members have continuing respon- sibility for the academic affairs of the school. The Committee is composed of the Chairpersons of the basic science departments of the Medical College Division and of the Programs of the Sloan-Kettering Division, the Directors of the Interdisciplinary Fields, the Dean and Associate Dean, the Provost for Medical Affairs of Cornell University, the Director and Associ- ate Director of the Sloan-Kettering Division, the Chairperson and Vice-Chairperson of the Faculty Ad- visory Committee (see below), and two non-voting, elected student representatives. The Executive Committee considers such matters in- volving the interests and policies of the Graduate School of Medical Sciences as are referred to it by the Faculty Advisory Committee, by individual members of the Faculty, or are generated upon its own initiative. The Committee approves the addition or deletion of fields of study, reviews the admission of students, approves student's major and minor fields, reviews the curriculum and requirements for degrees. The Executive Committee is chaired by the Dean, who is the academic administrative officer of the Graduate School of Medical Sciences and is aiso an Associate Dean of the Graduate School of Cornell University. The Secretary of the Executive Committee is the As- sociate Dean, who is also an Assistant Dean of the Graduate School of Cornell University. Faculty Advisory Committee The Faculty Advisory Committee is the primary body representing the views of the Faculty of the Graduate School of Medical Sciences. The Committee advises the Dean and the Executive Committee on the impact of educational and policy matters under their consider- ation and recommends changes in educational activities, procedures, and policy of the Graduate School of Medical Sciences. The Faculty Advisory Committee is composed of one elected faculty representative of each Field of the Medical College Division and of each Unit of the Sloan-Kettering Division, and one elected student rep- resentative from each Division. The Chairperson and Vice-Chairperson of the Committee are elected by its membership. Non-voting members are the Dean and Associate Dean, the Provost for Medical Affairs of Cornell University, and the Director and Associate Di- rector of the Sloan-Kettering Division. Admission Applications For admission to the Graduate School of Medical Sci- ences an applicant must (1) have a baccalaureate degree or the equivalent from a college or university of recognized standing, (2) have adequate preparation in the chosen field of study, and (3) show promise of ability to pursue advanced study and research, as judged by his or her previous record. Inquiries about graduate study should be addressed to the Dean of the Graduate School of Medical Sci- ences, 1300 York Avenue, New York, New York 10021 or to the Associate Director of the Sloan-Kettering Division, 1275 York Avenue, New York, New York 10021. Candidates may be admitted in September, February, or July, although places in the graduate program for February and July may not be available because of prior commitments to applicants for September admis- sion. Applicants for February or July admission should correspond directly with the respective Field Director in the Medical College Division or the Associate Direc- tor of the Sloan-Kettering Division regarding the availability of places. Application material must be completed and returned to the Office of the Dean together with (1 ) official transcripts of records from all colleges and universities attended, (2) a statement of purpose of graduate study, and (3) two letters of recommendation from individuals in academic positions who know the appli- cant professionally. In addition, scores from the Graduate Record Examinations are usually required by individual fields to aid in their evaluation. Applica- tion for taking the Graduate Record Examinations (GRE's), the Aptitude (Verbal and Quantitative) Test and the Advanced Test, must be made directly to the Educational Testing Service Graduate Record Examinations Box 955 Princeton, NJ 08541 The proper Institution Code Number to use in your GRE application for the Cornell University Graduate School of Medical Sciences (New York City) is R 2119-6. Applications for September or July admission and all credentials, including official transcripts of records from all colleges and universities attended, must be received by the deadline date of February 1. Applications and credentials for February admission must be received by November 1 . Application fee. A nonrefundable charge of $25 is made for filing an application for admission. The completed application and all supporting docu- ments are reviewed by the Field (or Division) Credentials Committee. Applicants who are consid- ered potentially acceptable are usually called for a personal interview. At the time of interview, after dis- cussing his or her interests with the members of the Field or Unit, the applicant may tentatively select a major sponsor. If accepted by the Field or Unit, an Degree Requirements 7 application is returned to the Dean who may refer it to the Executive Committee for final review and decision. A student is formally notified of acceptance for study in the Graduate School of Medical Sciences by a letter from the Dean. An applicant accepted for admission is requested to inform the Graduate School of Medical Sciences of her or his plan to either accept or refuse the offer of admission within one month after the Dean's acceptance letter has been received. It is the policy of Cornell University actively to support equality of educational and employment opportunity. No person shall be denied admission to any educa- tional program or activity or be denied employment on the basis of any legally prohibited discrimination in- volving, but not limited to, such factors as race, color, creed, religion, national or ethnic origin, sex, age, or handicap. The University is committed to the mainte- nance of affirmative action programs which will assure the continuation of such equality of opportunity. Admission policies are also in conformity with the policy of New York State in regard to the American ideal of equality of opportunity as embodied in the Education Practices Act. Categories An applicant is accepted by the Graduate School of Medical Sciences (1) as a degree candidate for the M.S. or Ph.D., or (2) as a provisional candidate. Provisional candidacy provides opportunity for a pro- spective degree candidate, whose educational preparation is difficult to evaluate, to begin graduate studies. On the basis of the record of accomplishment in the first half of the academic year, the adviser or temporary Special Committee of a provisional candi- date may recommena to the Dean that (1) provisional candidacy be changed to degree candidacy, (2) provi- sional candidacy be continued for the remainder of the academic year, or (3) provisional candidacy be termi- nated. A maximum of one academic year in the status of provisional candidacy is permitted and credit of a maximum of one residence unit may be allowed on petition, provided there is convincing evidence that performance has been of the same quality as that required of degree candidates. Special Students Special students are those students who are not de- gree candidates in either the Graduate School of Medical Sciences or the Medical College and who are given permission by the respective dean to take courses at either school. Special students must be degree candidates at other institutions and the courses taken at Cornell must be essential to their degree programs and are not offered by the institu- tions at which they are matriculated as degree candidates as certified by the institutions. Enrollment as a special student is not intended as preparation for admission to degree programs at Cornell or elsewhere. In the case of the Graduate School of Medical Sci- ences, special students are accepted only with the approval of the appropriate Field Director in the Medi- cal College Division or of the appropriate Chairperson in the Sloan-Kettering Division. Special students must demonstrate special qualifications in terms of prepara- tion and ability. They must register with the appro- priate office in the Graduate School of Medical Sci- ences or in the Medical College and must pay all tuition and fees before being permitted to attend lec- tures or laboratory sessions. Tuition is computed on the basis of the ratio of course hours taken to the total hours of instruction for the academic year (33 weeks of 40 hours). There is a registration fee of $25. Degree Requirements Major and Minor Fields* A candidate for the degree of Master of Science is required to register for study in one major and one minor field. Each field decides whether the Special Committee of a candidate for the Ph.D. degree must have two or three fields represented. Accordingly, a candidate for the degree of Doctor of Philosophy is required to register for study in one major and one or two minor fields. At least one of the minors must be outside the area of the major field. The Special Committee The general degree requirements of the Graduate School of Medical Sciences are minimal in order to give maximum flexibility in choosing a desirable pro- gram of study. The student's program is determined with the aid and direction of a Special Committee, consisting of at least three faculty members chosen by the student from those fields that best fit his or her areas of interest. Satisfactory progress toward a de- gree is judged by the committee rather than by arbitrary standards imposed by the Graduate School of Medical Sciences. There are no regulations of the Faculty of the Graduate School of Medical Sciences governing the specific content of instruction, courses, or grades to which the Special Committee must sub- scribe, except those imposed by the fields. The committee is primarily responsible for the candidate's development as an independent scholar and scientist. No later than four weeks after enrollment, a candidate must file a statement of the major and minor fields selected for study, after which the student must choose one faculty member to represent each field and to serve on a Special Committee. The faculty member representing the major field usually advises the student concerning the other selections and chairs the committee. At least one member of the committee must represent a field different from the candidate's major field. Members may agree to serve temporarily during the candidate's first year of residence until the candidate has had the opportunity to become ac- quainted with areas of research in the fields of his or her choice. On completion of this year of residence, a permanent Special Committee will be formed, the "Areas of concentration towards a degree at the Cor- nell University Graduate School of Medical Sciences are referred to as Fields in the Medical College Divi- sion and as Units in the Sloan-Kettering Division. Both these terms are intended to be covered by the term field in this and subsequent sections 8 Degree Requirements membership of which can be changed with agreement of all members of the old and newly formed commit- tees and the approval of the Dean. The members of the Special Committee decide on the student's pro- gram of study and research, and judge whether progress toward a degree is satisfactory. After con- sulting the other members, the chairperson of the Speciai Committee prepares term reports on the can- didate for submission to the Dean. The members of the committee serve on all the candidate's examining committees and they approve his or her thesis. Registration and Course Grades No student in the Graduate School of Medical Sci- ences may double-register for an advanced general or professional degree with any other school or college except the Cornell University Medical College. At the beginning of each term, students are required to register with the Office of the Graduate School of Medical Sciences and to file a registration of courses form indicating all courses they will take. A fee of $10 is charged for late registration. At the beginning of each course in which the student is enrolling, the student will complete a separate course registration form for the instructor. All courses for which the student registers for credit will be en- tered in the official record. Grades of graduate students are reported as: Excellent (E\ Satisfactory (S), Unsatisfactory (U), Incomplete (I), Absent (Abs.), or Unofficially Withdrawn (W). A grade of Incomplete or Absent cannot be changed later than one term following the one in which the course was taken. Registration for the summer is required of those grad- uate students who will be engaged in research. Residence The Faculty of the Graduate School of Medical Sci- ences regards study in residence as essential. Each candidate for an advanced general degree is expected to complete the residence requirements with reason- able continuity. A student must register each term from the time of his or her first registration in the Graduate School of Medical Sciences until the student either withdraws or completes a degree (unless a leave of absence has been granted). Full-time study for one-half academic year with satisfactory accom- plishment constitutes one residence unit. Two units of residence are the minimal requirement for the master's degree and six units are the minimum for the doctoral degree However, the time necessary to obtain the degree generally exceeds the minimal requirements. A candidate for the Ph.D. degree must spend two of the last four units of required residence in successive terms on the New York City or the Ithaca campus of Cornell University. No more than seven years may intervene between the time of first registration and the completion of all requirements for the doctoral degree. A student must complete all requirements for the mas- ter's degree m four years Part-time graduate study, if it is necessitated by off- campus employment noncontributory to the major field of study, is not encouraged Requests for part- time study must be reviewed by the Executive Com- mittee If permission is granted for part-time study, the student must be in residence at least half-time The legislation with respect to eligibility of part-time students for residence units is as follows: Employment Residence Units Allowable Per Half Academic Year Total clock Contrib- Noncon- Off hours per utory in tributory; campus week major field; on campus on campus 0-10 hrs. 1 unit 1 unit *4 unit 11-20 hrs. 1 unit unit % unit 21-30 hrs. ¥* unit 1 /2 unit (teaching unit (research)* * Time spent assisting in research, if it is contributory to the major field of study, shall be credited toward allowance of a full residence unit. Transfer of Residence Credit No residence credit will be granted for study outside the Graduate School of Medical Sciences to fulfill the requirements of the M.S. degree. No commitment can be made about granting residence credit toward the Ph.D. requirements for previous study in another grad- uate school until after the candidate has entered into residence at the Graduate School of Medical Sci- ences. At that time, the student's Special Committee may recommend acceptance of study outside the Graduate School of Medical Sciences to the Executive Committee, which will determine the number of resi- dence units to be awarded. No credit can be transferred for study undertaken as an undergraduate or as a special student even in courses designed for graduate students. A student who has satisfactorily completed two or more academic years of study toward the degree of M.D. at the Cornell University Medical College, or another accredited medical school in the United States with a curriculum equivalent to that of the Cor- nell University Medical College, may transfer a maximum of two units of residence credit after passing an evaluation examination administered by a commit- tee appointed by the Executive Committee of the Graduate School of Medical Sciences. Summer Research Registration is required for the summer research term whether or not this effort will be credited toward resi- dence unit accumulation. Students registered for summer research pay prorated tuition only if they are obtaining residence credit. However, no degree candi- date is eligible for more than two residence units in any period of twelve consecutive months. Study In Absentia A candidate for the degree of Doctor of Philosophy may petition for permission to earn residence units for study away from Cornell University while regularly reg- istered in the Graduate School of Medical Sciences. A candidate to whom this privilege has been granted may work temporarily under the immediate supervi- sion of an individual designated by his or her Special Tuition and Fees 9 Committee, but the candidate's program will continue to be directed by the Committee For study in absen- tia, not more than two residence units may be earned toward fulfillment of the minimal residence require- ments for the Ph.D. degree A student given leave for such study must register as a candidate in absentia. Leave of Absence A candidate who finds it necessary to interrupt the continuity of his or her residence must petition the Dean for an official leave of absence This written petition must specify the term of absence, state the reason for the requested leave of absence, and be approved by the student's Special Committee. A student who will not be in residence but will return to the Graduate School of Medical Sciences to present and defend a thesis at the final examination, having completed all requirements for a degree except for the final examination, must petition for a leave of absence. Examinations Three examinations are required by the Faculty of the Graduate School of Medical Sciences: (1) Final Exam- ination for the M.S. Degree, (2) Examination for Admission to Doctoral Candidacy, and (3) Final Exam- ination for the Ph.D. Degree. Examinations are administered by an Examining Committee consisting of a chairperson appointed by me Dean, the members of the candidate's Special Committee, and, in the case of the Admission to Candidacy Examination, three additional members selected from the Faculty of the Graduate School of Medical Sciences and or of other institutions. In addition to these examinations, the can- didate's major field may require a qualifying examination as part -'>f its evaluation of the candidate after two units of residence have been completed. For the M.S. degree: The Final Examination may be oral or both oral and written. For the Ph.D. degree: The Admission to Candidacy Examination is both oral and written and certifies that the student is eligible to present a thesis to the Faculty of the Graduate School of Medical Sciences. The examination should be taken after course work is largely finished but before significant thesis research has begun. Accordingly, the usual examination time will be at the end of the second year of residence. The examination may not be taken until two units of resi- dence credit have been accumulated and a minimum of two units of residence credit is required after pass- ing this examination before the final examination can be scheduled. The final examination for the Ph.D. degree is an oral defense of the candidate's thesis. It must be passed within four years after completion of the required residence units, or within seven years from the date of first registration, whichever is earlier. Foreign Language Requirements Each field of study has its own foreign language re- quirements. The student's Special Committee may require knowledge of foreign languages beyond the requirements of the fields listed in this Announcement. Arrangements for a foreign language examination will be made on application to the Office of the Dean. As an alternative to this examination, the candidate may demonstrate proficiency by having passed the reading part of the language qualification tests administered by the College Entrance Examination Board Theses A principal requirement for both the M.S. and the Ph.D. degrees is the presentation of a thesis con- stituting an imaginative contribution to knowledge Ordinarily, the thesis is written on a research topic in the candidate's major field of study, under the direction of the chairperson of his or her Special Committee The faculty requires that the Ph.D. thesis be published in abstract and be recorded on microfilm. Tuition and Fees Tuition Tuition for a student regularly matriculated in the Grad- uate School of Medical Sciences is $8,900 for the academic year 1983-84 and is payable in two equal parts, the first of which is due at initial registration. Tuition includes fees for matriculation, hospitalization insurance, graduation, and miscellaneous thesis expenses. For graduate students who (1) have been in continu- ous residence at Cornell in the same doctoral program and have accumulated four units of residence credit, (2) have passed their Admission to Candidacy Exarr ination, and (3) are not taking courses in the Medical College curriculum, a reduced charge of $1800 per annum ($900 per semester) will be made for tuition and fees for the terms subsequent to the Admission to Candidacy Examination. For those students who are accepted into the Ph.D.-M.D. Program (see p. 30) and will continue to take courses in the medical curricu- lum, an additional tuition charge, based on the Medical College tuition ($12,650 per annum), will be made for the medical course hours taken. A student who is to receive partial residence credit (see p. 8) because of employment should apply for proration of tuition on forms obtainable at the Office of the Dean. Proration of tuition does not apply to the special reduced tuition of $900 per semester. Other Fees In Absentia A graduate student registered in absen- tia pays a fee of $200 each term, and may continue hospitalization insurance by payment of the annual premium directly to the Student Accounting Office. If students in absentia take advantage of local priv- ileges, such as the use of the library, desk space, Student Health Service, and Cornell housing, the fee is $400 per semester. The latter fee also covers hospi- talization insurance. Leave of Absence Doctoral graduate students filing leaves of absence will be required to pay an active-file fee of $200 for each semester, up to a maximum of six semesters ($1,200), during which they are not regis- tered with the Graduate School. This fee will not be subject to finance charges but must be paid before the student can receive an advanced degree Petition for waiver of this fee will be considered for students who 10 Financial Assistance have not completed the required number of residence units. Candidate for Degree Only A graduate student who returns to the University to present a thesis and to take the final examination for an advanced degree, all the work for that degree having been previously completed, must register as a Candidate for Degree Only and pay a fee of $35 unless the student has paid the active-file fee during the semester in which the final examination is taken. A graduate student who has previously fulfilled all other degree requirements, who has been granted a leave of absence, and who returns to the Graduate School of Medical Sciences to present a thesis and to take the final examination must register as a Candi- date for Degree Only and pay a fee of $35. Any individual who owes money to the University will not be allowed to register or reregister in the Univer- sity, receive a transcript of his or her record, have his or her academic credits certified, be granted a leave of absence, or have a degree conferred. The amount, time, and manner of payment of tuition, fees, or other charges may be changed at any time without notice. Refunds Part of the amount personally paid for tuition will be refunded if the student obtains official certification of leave of absence or withdrawal from the Graduate School of Medical Sciences during the semester. Stu- dents who terminate their registration during a regular term in this manner will be charged tuition from the registration day to the effective date of the certificate as follows: first week, 10 percent; second week, 20 percent; third week, 30 percent; fourth week, 40 per- cent; fifth week, 60 percent; sixth week, 80 percent; seventh week, 100 percent. No charge will be made if the effective date of leave or withdrawal is within the first six days of the term, including registration day. Financial Assistance All applicants to the Graduate School are requested to submit a Graduate and Professional School Financial Aid Service (GAPSFAS) form providing an estimate of financial need. The information will be used in two ways: The number of students with documentable need will allow the University to obtain maximum federal funding for loans and work-study purposes, and the specific need of an applicant may be used to determine that individual's graduate support. Please obtain the necessary form, available at your college or university financial aid office and from the Educational Testing Service File the form with the Educational Testing Service, Box 2614, Princeton, New Jersey 08541, and request that the information be sent to Cornell-Code 2267. Financial assistance is available to qualified appli- cants. Individual fields may offer predoctoral research fellowships, research assistantships, or teaching as- sistantships. These positions may provide a stipend in addition to tuition Information about these positions may be obtained directly from the field or unit at the time of application. Nationwide competitive predoctoral fellowships are available from the National Science Foundation and the National Research Council. Information about these fellowships should be requested directly from the appropriate governmental agency. New York State residents are eligible for several pre- doctoral fellowships and the Tuition Assistance Program, which assists in tuition payments. Applica- tion forms may be obtained from the New York Higher Education Services Corporation. Student Financial Aid Section, Tower Building, Empire State Plaza, Albany, New York 12255. Several loan programs are available to graduate stu- dents. Under these programs, repayment of the principal amount of the loan together with the interest on the loan may be deferred until after graduation. Complete information regarding loan programs may be obtained from the Graduate School Office. Opportunity for part-time employment is often avail- able in departmental research projects or other activities. Applications should be made directly to indi- vidual departments. The Graduate School of Medical Sciences participates in the Work-Study Program of Cornell University. For the 1983-84 academic year, the maximum contribution to a student's salary is $3,450 of matching funds. Scholarships and Awards Graduate School Scholarships. The Office of the Dean of the Graduate School of Medical Sciences administers tuition scholarships to students in the Medical College Division from funds generously made available by the Dean of the Medical College. The award of these tuition scholarships is made on the recommendations of the Field Directors in the Medical College Division. Tuition scholarships and fellowships are available to graduate students in the Sloan-Ketter- ing Division through the Office of the Associate Director of the Sloan-Kettering Division. The Vincent Astor Scholarship Fund. Funds for limited tuition assistance are also derived from the income from a generous gift by the Vincent Astor Foundation to the Graduate School of Medical Sci- ences and to the Medical College. Allocation of these funds for graduate student tuition assistance is made at the discretion of the Dean of the Graduate School of Medical Sciences on the recommendations of the Field Representatives in the Medical College Division and of the Associate Director of the Sloan-Kettering Division. The Lois and Max Beren Foundation may award a scholarship to a promising student accepted for ad- mission at Cornell University Medical College in an amount to be determined by consultation between the college and the foundation The student shall be se- lected by the college, subject to the approval of the foundation, and may be a candidate for either the Ph.D. or M.D. degree. It is the desire of the foundation to assist a student who possesses a great eagerness to pursue studies but who would find it impossible or impractical to do so without the financial support of the foundation. Student Health Services 11 The Elizabeth C. Lowry Scholarship Fund was en- dowed by Dr. Lowry, a member of the class of 1935, in memory of her late husband, Dr. Thomas Lowry, who was also a member of that class. The income is to be used to provide financial assistance to women stu- dents in the Medical College. If, in any year, there is no woman student in need of such assistance, the income available may be awarded to a woman candi- date for a Ph.D. in the Graduate School of Medical Sciences. The Frank R. and Blanche A. Mowrer Memorial Fund. Limited financial assistance is available from the income of this fund to one student per year en- rolled in the Ph.D.-M.D or M.D.-Ph.D. program. The Frank Lappin Horsfall Jr. Award is endowed by funds provided in memory of Dr. Horsfall by his many friends and family. It is continued evidence of his concern for students manifest during his directorship of the Sloan-Kettering Division. The award is available annually to a student of the Sloan-Kettering Division, who in the opinion of the Committee of the Faculty of the Sloan-Kettering Divi- sion, has been most distinguished, especially in the Admission to Doctoral Candidacy Examination. The Julian R. Rachele Prize. The income of a fund established by Dr. Julian R. Rachele, former Dean of the Cornell University Graduate School of Medical Sciences, provides for an annual prize to be awarded to a candidate for the Ph.D. degree for a research paper of which the candidate is the sole or the senior author and which has been accepted during the twelve-month period ending 30 April for publication in a scientific journal representing one of the fields of the Graduate School of Medical Sciences. In order to qualify for the prize, a student must have passed the Admission-to-Candidacy Examination. A candidate for the prize must submit a copy of the manuscript to the Dean by 3u April for evaluation by an ad hoc committee appointed by the Dean. Man- uscripts received after 30 April will be considered for the award in the subsequent year. Student Health Services The Student Health Plan of Cornell University Medical College provides hospitalization and major medical insurance for all graduate students. In addition, the Plan provides for ambulatory care at the Personnel Health Service of The New York Hospital-Cornell Med- ical Center. Physicians at the Health Service will refer students who require specialized care to clinics of the Hospital and to attending physicians of the staff. The cost of medical services provided by the Plan are included in the tuition and fee structure announced by the College each academic year Students will be issued Plan membership cards and will receive cour- tesy privileges at The New York Hospital Pharmacy. Entering students are requested to have a physcial examination, chest X-ray and laboratory tests per- formed by their personal physicians prior to matriculation. The hours of the Personnel Health Serv- ice and a complete statement of Plan benefits will be provided to each graduate student. The College recommends that students purchase in- surance coverage for eligible dependents who do not have other insurance available to them. Insured de- pendents are not eligible for care at the Personnel Health Service but they will be referred to appropriate members of the Hospital staff for medical treatment. A student on leave for study in absentia may continue hospitalization insurance by payment of the annual fees directly to the Student Accounting Office. A student on a leave for reasons other than study in absentia is not eligible to receive student health benefits. Residence Halls F. W. Olin Hall, a student residence, is at 445 East Sixty-ninth Street directly across from the Medical Col- lege entrance on York Avenue. Olin Hall contains a gymnasium, lounge and 174 residence rooms. Each residence room is furnished as a single bedroom- study, but since two rooms share a connecting bath, they may be used as a suite for two students. The rooms are completely furnished. The student housing fee is $1,620 for the 10-month academic year, $1,944 for the calendar year, or for shorter periods $162 per month. Livingston Farrand Apartments, also located on East Sixty-ninth Street just beyond Olin Hall, have furnished apartments of 1V2, 2, 3, and 4 rooms. Cook- ing facilities are provided in these apartments and housing fees in these buildings range from $200 to $378 per month (utilities not included). Apartments in these facilities are available to married students and upperclasspersons Jacob S. Lasdon House, an apartment residence, is located at 420 East Seventieth Street. This building contains studio, one-bedroom, and two-bedroom apartments and two squash courts. Apartments are fully furnished and housing fees range from $356 to $618 per month including utilities. Single, first-year students cannot be accommodated in this building. The fees listed above may be changed at any time without previous notice. 13 Cornell University Fields of Instruction Instruction at the Medical College Division Biochemistry Faculty J. P. Blass, A. L. Boskey, E. Breslow, A. J. L. Cooper, J. Cornell, T. Duffy, G. F. Fairclough, J. D. Gass, H. Gilder, J. Goldstein, O. W. Griffith, D. Hajjar, R. H. Haschemeyer, B. Horecker, C.-Y. Lai, P. W. Melera, A. Meister, U. Muller-Eberhard, A. Novogrodsky, A. S. Posner, J. R. Rachele, R. R. Riggio, A. L. Rubin, B. Saxena, E. T. Schubert, R. L. Softer, K. H. Stenzel, S. S. Tate, P. P. Trotta, S. Udenfriend, D. Wellner, K. Woods, D. Zakim Field Director A. Meister, Department of Biochemistry, Room E-106, Medical College, (212) 472-6212 Faculty Representative D. Wellner, Department of Biochemistry, Room E-219, Medical College, (212) 472-6197 Graduate instruction is offered leading to the Ph.D. degree. Within the framework of degree requirements and in consultation with the student, the course of study is planned to fit the needs of the individual. Although formal course work is required, emphasis is placed on research. Research opportunities exist in various areas of biochemistry including enzymology, structure and function of proteins and nucleic acids, molecular biology, physical biochemistry, and the inter- mediary metabolism of amino acids, carbohydrates, nucleic acids, and lipids. Entering graduate students usually work for short periods in several of the labora- tories of the faculty members of the Field before beginning their thesis research. Students are encour- aged to choose challenging fundamental research problems that are on the frontiers of biochemistry. The laboratories of the faculty members are equipped with virtually all of the instruments and facilities re- quired for modern biochemical research; thus, graduate students are instructed in such methodology as chromatography, countercurrent distribution, radio- active and stable isotope techniques, spectropho- tometry, electrophoresis, and analytical ultracentrifugation. Students who undertake graduate study in biochemis- try must have a sufficiently comprehensive background in chemistry to pursue the proposed course of study and must present evidence of knowl- edge of biology, general experimental physics, mathematics (including differential and integral cal- culus). Students may remedy deficiencies in these areas during the first year of graduate study. The Graduate Record Examinations (the Aptitude Test and the Advanced Test in chemistry) are ordinarily required. The language requirement for the Ph.D. and the M.S. degrees is proficiency in one modern foreign language acceptable to the student's Special Committee. Profi- ciency in a computer programming language, as demonstrated by executing a meaningful program, may substitute for proficiency in a foreign language. Students are encouraged to complete applications for fall admission before the preceding February 1. Special Interests of the Faculty J. P. Blass: Genetic and metabolic aspects of neurochemistry A. L. Boskey: Mechanisms of biological calcifications; role of phospholipids and proteoglycans in bone and tooth formation; structural studies of hard tissue by X-ray crystallography and electron microscopy E. M. G. Breslow: Structure-function relationships in the interactions between posterior pituitary proteins and hormones; protein-protein and metal ion- protein interactions A. J. L. Cooper: Ammonia, amino acid and a- keto acid metabolism in the brain; use of 13 N isotopic tracers in brain metabolic studies J. S. Cornell: Biochemistry of reproduction; protein chemistry of the placenta; endocrine influences in gestational diabetes and toxemia of pregnancy; an- terior pituitary hormones T. E. Duffy: Neurochemistry; carbohydrate and energy metabolism in altered functional states of brain: ammonia detoxification and hepatic coma: bio- chemistry of developing brain G. F. Fairclough: Clinical biochemistry; pulmonary sur- factant biosynthesis; lipoprotein structure and function J. D. Gass: Mechanism of enzyme action; application of computers to biological problems H. Gilder: Pulmonary lamellar bodies and surfactant, lung lipid synthesis, evaluation of surfactant in etiol- ogy of oxygen toxicity, metabolic response to surgery, experimental shock J. Goldstein: Structure-function of red cell surface anti- gens; cell surface and differentiation; protein synthesis O. W. Griffith: Design and synthesis of enzyme spe- cific substrates and inhibitors; in vivo manipulation 14 Instruction— Medical College Division of metabolic pathways; enzyme mechanisms; sulfur amino acid metabolism D. Hajjar: Lipid metabolism; study of the pathogenesis of cardiovascular disease induced by viruses and endothelial injury R. H. Haschemeyer: Structure of fibrinogen; subunit interactions in proteins; electron microscopy of mac- romolecules; lipoprotein and membrane structure; computer simulation and numerical analysis B. L. Horecker: Intermediary metabolism; structure- function relationships in biomolecules C. -Y. Lai: Structure-function relationships of proteins, bacterial toxins and enzymes; macromolecular in- teractions involving membranes or membrane enzymes; protein and peptide structural chemistry; protein catabolism P. W. Melera: Gene amplification; mechanisms of anti- folate drug resistance; molecular genetics A. Meister: Enzymology; amino acid metabolism and its relationships to human disease U. Muller-Eberhard: Hepatic drug metabolism A. Novogrodsky: Lymphocyte activation and cell-cell interactions; cellular and transplantation immunology A. S. Posner: Crystal chemistry; ultrastructural bio- chemistry; atomic structure of bone; hard-tissue chemistry R. R. Riggio: Transplantation: biochemistry of immu- nologic phenomena associated with humoral sensitization of transplantation antigens; and al- lograft tolerance A. L. Rubin: Transplantation; autoimmune disease, cellular biochemistry B. Saxena: Chemistry, measurement, and mechanism of action of pituitary protein hormones; structure- function and hormone-receptor interaction of gonadotropins E. T. Schubert: Enzyme studies of the developing kidney, clinical biochemistry R. L. Softer: Angiotensin-converting enzyme; amino- acyl-tRNA-protein transferases; studies of mem- brane-bound enzymes K. H. Stenzel: Cell proliferation and differentiation S. S. Tate: Plasma membrane enzymes; metabolism and physiology of hypothalamic releasing hormones P. P. Trotta: Molecular basis of the immunodeficiency diseases; biochemistry of colon cancer; structure- function relations in adenosine deaminase S. Udenfriend: Elucidation of the pathways of en- kephalin biosynthesis and determination of the structure of proenkephalin D. Wellner: Mechanisms of enzyme action; enzyme kinetics; protein structure K. R. Woods: Physical-chemical understanding of human blood fractions; blood coagulation, structure of antibodies; interferon synthesis and structure D Zakim: Membrane biochemistry; function of UDP- glucuronyltransferases Courses 1. Graduate Biochemistry Offered jointly by the fac- ulties of the Medical College and Sloan-Kettering Divisions. Details are given on p. 30 under Inter- divisional Course. 2. Introduction to Research Experimental bio- chemistry dealing with the isolation, synthesis, and analysis of substances of biochemical importance (en- zymes, coenzymes, various metabolites, and intermediates), and study of their properties by various chemical and physical techniques. The student ob- tains this varied research experience by spending approximately two months in the laboratory of each of four faculty members of his or her choice. For incom- ing graduate students majoring in biochemistry. The staff. 3. Selected Topics in Biochemistry Advanced study in selected topics is offered in areas such as (1) nucleic acids and protein synthesis; (2) intermediary metabolism; (3) kinetics and enzyme mechanism; (4) protein chemistry; (5) structure of membranes and the biochemistry of transport; (6) hormones; and (7) mi- croprotein and peptide chemistry. Generally, one or two of these courses is offered yearly in the third trimester. The staff. 4. Advanced Biochemistry The course consists of a series of lecture units (minicourses) covering topics such as size, shape, and structure of macromolecules; molecular biology; information transfer; membrane structure and function; hormones; enzyme structure and function; antimetabolites in chemotherapy; and other subjects of current research interests. These subjects are taught at an advanced level with particu- lar attention to contributions of recent research. It is not essential that students take the lecture units in any particular sequence. Minimal prerequisite: Biochemis- try (described above) or its equivalent. Wirier and spring trimesters. S. S. Tate, and staff. 5. Physical Methods This course consists of a se- ries of workshops including laboratory demonstrations and lectures and/or tutorials in physical techniques for the study of macromolecular and cellular structure. Examples of techniques available for study are: hydro- dynamic and equilibrium methods, electron microscopy and other optical methods, resonance methods, and separation techniques such as chro- matography, electrophoresis, iso-electric focussing, affinity methods. Time and place must be arranged with the faculty members in charge. Prerequisites: Graduate Biochemistry or its equivalent and Physical Chemistry. First trimester. Cell and Developmental Biology Faculty R. Bachvarova, D. M. Bader, C. G. Becker, J. M. Bedford, D. Bennett, C. Bianco, A. L. Boskey, D. C. Brooks, P. G. Bullough, D. A. Fischman, F. G. Girgis, J. Goldstein, B. Hosein, B. B. Kaplan, C. R. Minick, R. Nachman, J. D. Pardee, M. S. Risley, T. C. Rodman, B. Saxena, E. T. Schubert, J. L. Sirlin, G. W. Siskind, R. C. Swan, S S. Wachtel, B. B. Weksler Field Director D. A. Fischman, Department of Cell Biology and Anat- omy, Room A-116, Medical College, (212) 472-6400 Faculty Representative J. L. Sirlin, Department of Cell Biology and Anatomy, Room A-229, Medical College, (212) 472-6418 Instruction— Medical College Division 15 Graduate study in the Field of Cell and Developmental Biology leads to a Ph. D. degree and emphasizes the basic relationships between structure and function of biological systems at all levels of organization. Thus the Field is fundamentally concerned with the nature, development, and functional modulation of biological systems, as well as significance of configuration, pat- tern, and other spatial relations in biological systems. The scope of interest extends from the molecular level to that of the whole organism and embraces normal as well as pathological structure. Opportunities for research training include the inves- tigation of cellular fine structure using such techniques as light and electron microscopy, isolation and analy- sis of cellular subtractions by differential ultracentrifugation, cytochemistry, molecular bio- chemistry, and enzymology. For graduate study in the Field, adequate undergradu- ate preparation in biology, chemistry (including organic chemistry), physics, and mathematics is recom- mended. Requirements for admission are flexible in proportion to the promise and accomplishments of the applicant. Applicants are requested to present the re- sults of the Graduate Record Examinations. Requirements for minor sponsorship in the Field will be arranged with individual students, but research experience in the minor sponsor's laboratory is strongly encouraged. In addition to the courses listed below, appropriate courses for graduate students in the Field are Bio- chemistry, Physiology, and those courses given by the Field of Neurobiology and Behavior. A reading knowledge of a foreign language is desirable. The Field requires a qualifying examination at the end of the first year of residence. At the discretion of the examining committee, the examination may be written, or oral, or both. The Admission to Candidacy Exam- ination required by the Graduate School of Medical Sciences must be taken before six units of residence credit have been accumulated and before substantial progress has been made in the candidate's thesis research. Special Interests of the Faculty R. Bachvarova: Molecular developmental biology D. M. Bader: Cell biology of myogenesis C. G. Becker: Cardiovascular and renal disease; immunopathology J. M. Bedford: Physiology of mammalian gametes and reproductive tract D. Bennett: Mammalian genetics, with special refer- ence to genetic regulation during early embryonic development C. Bianco: Cell biology of leucocytes; proteins of the complement and of the coagulation system in monocyte function A. L. Boskey: Structural studies of hard tissue by x-ray crystallography and electron microscopy D. C. Brooks: Brain stem influences upon the visual system P. G. Bullough: Diseases and metabolism of bone D. A. Fischman: Cell and developmental biology of skeletal and cardiac muscle; cytoskeletal organiza- tion and function F. G. Girgis: The cranial and facial sutures, their de- velopment, structure, and the analysis of sutural position; of particular interest are factors inducing chondrogenesis in the cranial vault J. Goldstein: Modification of erythrocyte cell suface structure; cell growth effectors B. H. Hosein: Effects of phorbolesters on differentia- tion of cultured epithelial cells B. B. Kaplan: Gene activity and its regulation in brain and cells of neuroectodermal origin C. R. Minick: Pathogenesis of arteriosclerosis and hy- pertension; immunopathology; electron microscopy R. L. Nachman: Biology of platelets J. D. Pardee: Biochemical mechanisms of cell motility and cytokinesis; regulation of actin assembly M. S. Risley: Chromosome structure during sper- matogenesis; in vitro differentiation of spermatogenic cells; gene expression during spermatogenesis T. C. Rodman: Analytical cytology of cell nuclei; cytogenetics B. Saxena: Chemistry, measurement, and mechanism of action of pituitary protein hormones E. T. Schubert: Enzyme studies of the developing kidney; investigation of renal dysfunction at enzyme level J. L. Sirlin: Mammalian reproductive biology G. W. Siskind: Immunology; ontogeny of immune re- sponse; antibody heterogeneity R. C. Swan: Assembly of striated muscle filaments S. S. Wachtel: Immunogenetics; sex determination B. B. Weksler: Cell biology of platelets Courses 1. Cell Biology and Microscopic Anatomy Offered by the Staff of the Field of Cell and Developmental Biology, Medical College Division, in conjunction with the Department of Cell Biology and Anatomy, Medical College. This course follows a cellular and differentia- tive approach aimed at understanding the structure- function correlates that characterize the different tissues and organs. Selected topics are presented in the lectures and laboratory exercises to indicate a pattern of study and depth of analysis that the student can be expected to apply to the study of cells and tissues. A microscope slide collection, presenting tissues and organs in a variety of physiological and developmental states, as well as correlative electron micrographs are provided for individual study in the laboratory. Students must provide their own com- pound microscopes through their departments or sponsors. First and second trimesters. A required component of the course for all graduate students is a 2 hour, weekly seminar (time to be arranged) focuss- ing on detailed analysis of original literature, pertinent methods and unresolved questions related to topics in cell and developmental biology. Lectures: T TH 10-11. F 9-10. Laboratory: T TH 11-1, The staff. 2. Gross Anatomy Regional anatomy is studied principally through dissection of the human body. Supplementing this technique are prosections by in- structors, tutorial group discussions, and radiographic and endoscopic demonstrations. Enrollment is limited and students should consult the staff early in order to determine the availability of places. First and second trimesters. The staff. 16 Instruction — Medical College Division 3. Current Topics in Cell and Developmental Biol- ogy. Advanced topics in selected areas of cell, molecular and developmental biology will be explored in 2 hour weekly seminars. One hour of each session will be a didactic presentation by a faculty member followed by one or two student presentations of se- lected research papers. Representative topics will include: cell motility, the cytoskeleton, differential gene expression, membrane biogenesis and recycling, and chromatin organization. Each topic will be explored over a four week period. W 2-4, second and third trimesters. Drs. Fischman, Bachvarova and staff. 4. Workshop in Electron Microscopy. A lecture and laboratory course designed to acquaint graduate students with practical aspects of transmission and scanning electron microscopy. Lectures will cover basic theory of electron optics, tissue fixation, thin sectioning, staining, critical point drying, shadowing of protein and nucleic acids, and negative staining. A laboratory project and report will be required of all students. Enrollment is limited and students should consult Mr. Dennis to determine the availability of places. A laboratory fee of $300 will be required of all students. Third trimester, Th 1-5, Mr. Dennis and staff. Genetics Faculty F. H. Allen, V. G. Allfrey, K. Artzt, R. Bachvarova, D. Bennett, J. L. Biedler, E. A. Boyse, R. S. K. Chaganti, B. S. Danes, B. Dupont, J. L. German III, L. H. Graf, Jr., M. Hoffman, P. Hoffman, E. Johnson, R. M. Krug, G. Litman, P. W. Melera, L. J. Old, T. C. Rodman, P. Rubenstein, N. Sarkar, M. Scheid, J. R. Shapiro, F. W. Shen, S. Silagi, M. Siniscalco, J. L. Sirlin, J. Stavenzer, R. Sterner, S. Wachtel Field Director Lloyd H. Graf, Jr., Laboratory of Cell Genetics, Depart- ment of Obstetrics and Gynecology, Room S-519, Medical College, (212) 472-5729 Faculty Representative James L. German III, New York Blood Center, 310 E. 67th Street, New York, N.Y 10021, (212) 570-3075 The Field of Genetics is one of the two Interdiscipli- nary Fields of the Graduate School of Medical Sciences. The principal goal of the Field's training program is to provide students with a conceptual foun- dation for analyzing genetic systems and questions and with the range of laboratory skills needed to apply powerful modern experimental approaches. The diver- sity of interests and institutional affiliations (e.g., the Medical College, The Sloan-Kettering Division, Rockefeller University, The New York Blood Center) encompassed by the large Field Faculty gives stu- dents access to a great variety of outlooks and research environments. Within broad limits students pursue their own programs and interests in this framework The usual prerequisites for admission to graduate study for an advanced degree in genetics are under- graduate work in chemistry or biology, and courses in general genetics, general chemistry, organic chemistry, general biology, general physics, and math- ematics through calculus. Applicants are required to present Graduate Record Examinations scores in the Aptitude Tests and in the Advanced Test in chemistry or biology. Courses generally required of Genetics majors are those numbered 1 through 3 below, Graduate Bio- chemistry (see Interdisciplinary Courses) and Microscopic Anatomy (see Field of Cell and Develop- mental Biology). Introduction to Modern Genetics, number 4 below, being organized for 1983-84, is rec- ommended. Students are also encouraged to take Advanced Virology, offered by the Field of Microbiol- ogy, to avail themselves of genetics-related courses offered by the Sloan-Kettering Division and by Rock- efeller University, and to take advantage of the rich and varied seminar programs offered by institutions in the immediate area. Students are expected during their first year to spend time and perform experiments in the laboratories of three faculty members of the Field of Genetics. Students minoring in genetics may be required to take two semesters of the Genetics Seminar and Advanced Genetics. A limited period of work in the laboratory of the minor sponsor is recommended. An oral Qualifying Examination is required at the end of the first year of residence, and the Admission to Candidacy Examination must be taken at the end of the second year of graduate work. Special Interests of the Faculty F. H. Allen: Immunogenetics of blood groups V. G. Allfrey: Cell nucleus chemistry, chromosomal proteins; genetic control K. Artzt: Genetics of embryonal tumors R. Bachvarova: Developmental molecular biology D. Bennett: Mammalian developmental genetics; immunogenetics J. L. Biedler: Somatic cell genetics and cytogenetics E. A. Boyse: Mammalian immunogenetics R. Chaganti: Human cells; cell genetics B. S. Danes: Somatic cell genetics (with particular emphasis on human genetic metabolic errors) B. Dupont: Human immunogenetics J. L. German: Mammalian cell genetics and cytogenetics L. H. Graf, Jr.: Cell and molecular genetic study of differentiation in culture M. Hoffmann: H-2 immunogenetics P. Hoffman: Role of kinases and histones in genomic structure and gene expression E. Johnson: Eukaryotic gene expression and packaging R. M. Krug: Viral and molecular genetics G. Litman: Immunogenetics P. W. Melera: Molecular eukaryotic genetics L. J. Old: Tumor immunology and virology T. C. Rodman: Cytogenetics with emphasis on mecha- nisms of genetic control P. Rubenstein: Immunogenetics; histocompatibility; genetics; immunology, immunohematology N. Sarkar: Viral genetics and morphology of RNA oncogenic viruses M. P. Scheid: Lymphocyte development; immuno- genetics, defects, therapy J. R. Shapiro: Neuro-oncology Instruction — Medical College Division 17 F. W. Sheii : Immunogenetics of the mouse S. Silagi: Gene action and cellular differentiation in culture M. Siniscalco: Somatic cell genetics, vertebrate ge- nome organization, heritable disease J. Sirlin: Molecular biology of brain function J. Stavnezer: Molecular study of structure and re- arrangement of immunoglobulin genes R. Sterner: Biochemistry of HMG chromatin proteins, in vitro modification of nuclear proteins, and gene expression S. Wachtel: Immunogenetics of sex determination Courses 1. Genetics Seminar The topics and sponsors for the Genetics Seminar will be announced at a later time. The seminar is normally scheduled to be given on Mondays from 3-5 p.m. during the first, second and third trimesters. 2. Genetics Journal Club An informal meeting of students and staff at which current literature or re- search is discussed. Held every two weeks throughout the year. F 12. R. Bachvarova and/or L. Graf. 3. Advanced Genetics Designed to give the student a sound background in genetic theory; an in-depth consideration of the gene as a unit of heredity. Sched- uling for 1983-84 remains to be arranged. 4. Introduction to Modern Genetics Lectures by Genetics faculty on research concepts and meth- odologies in the areas of gene cloning, molecular probes and in vitro mutagenesis. Second trimester, time to be arranged. 5. Karyotyping Practical experience in chromosome analysis in the laboratory. Introduction to tissue culture techniques. Limited to two students. Third trimester: one day a week for seven weeks; hours to be ar- ranged. J. L. German. Microbiology Faculty R. W. Dickerman, T. C. Jones, J. S. Keithly, S. R. Meshnick, W. M. O'Leary, R. B. Roberts, C. A. Santos- Buch, L. B. Senterfit, G. W. Siskind, K. H. Stenzel, D. H. Sussdorf, M. E. Weksler, M. E. Wiebe Field Director W. M. O'Leary, Department of Microbiology, Room B-202, Medical College, (212) 472-6540 Faculty Representative R. W. Dickerman, Department of Microbiology, Room B-204, Medical College, (212) 472-6189 The Field of Microbiology offers graduate training leading to the Ph.D. degree. Under special circum- stances, candidacy towards the M.S. degree will be considered. Candidates may select an area of re- search from such microbiological topics as general and medical bacteriology, microbial chemistry and physiology, immunology and virology, and parasitology. Prospective students should complete at the under- graduate level a minimum of one year (or its equivalent) in general chemistry, organic chemistry, general physics, mathematics (including college al- gebra), botany or zoology (preferably both), and one semester or its equivalent of analytical or quantitative chemistry. General microbiology or bacteriology and calculus are strongly recommended. Students who have not completed the above requirements may be admitted to graduate study on the condition that deficiencies be corrected soon after admission. Appli- cants are ordinarily required to present Graduate Record Examinations scores for the Aptitude Tests and for the Advanced Test in chemistry or biology. Individual programs are determined by the student's Special Committee, composed of faculty members representing the major and minor fields. Students ma- joring in microbiology select their primary courses from those listed below. The nature and number of other courses that may be taken at this institution or at nearby universities will depend on the students' minor fields, their research activities, their individual inter- ests, and the advice of the Special Committees. All students majoring in microbiology are required to as- sist in the teaching of courses offered by the Field. Students majoring in other fields who elect to minor in microbiology are ordinarily required to take the course Microbiology and an Introduction to Infectious Dis- ease. In addition, students are required to enroll in an advanced course in microbiology or participate in a research project in the laboratory of their minor spon sors. In general this research is expected to take one to three months to complete, depending upon whether the project is pursued on a full-time or part-time basis. Ph.D. candidates are required to be proficient in one modern foreign language acceptable to their Special Committees. Although a qualifying examination is not ordinarily given, a student's Special Committee has the preroga- tive of requiring it. The Admission to Candidacy Examination is administered by a committee consist- ing of a chairperson appointed by the dean, the student's Special Committee, and three additional fac- ulty members. The written portion of this examination tests for basic facts and concepts in the candidate's area of study and for the candidate's problem-solving ability within and across disciplinary boundaries. The oral examination provides an opportunity for the stu- dent to correct deficiencies in the written examination, to be examined further on general knowledge, and to discuss and be questioned on his or her planned or current research. Special Interests of the Faculty R. W. Dickerman: Involvement of birds and mammals in the ecology of viruses pathogenic to man T. C. Jones: Intracellular parasitism; macrophage function; immune responses to protozoa J. S. Keithly: Factors influencing infectivity and vir- ulence of parasitic protozoa; testing antimetabolites against blood protozoa S. R. Meshnick: Adaption of infectious protozoa to intracellular survival; design of antiprotozoal agents W. M. O'Leary: Microbial composition; mechanisms of pathogenesis; antibiotic function; instrumental characterization of bacteria; infectious infertility 18 Instruction— Medical College Division R. B. Roberts: Interactions between microorganisms and phagocytic cells C. A. Santos-Buch: Parasitic diseases; immunopathol- ogy; cardiovascular disease L. B. Senterfit: Antigenic structure of mycoplasma; pathogenesis of respiratory viral and mycoplasmic disease; vaccine development; clinical microbiology G. W. Siskind: Regulation immune response, es- pecially anti-idiotype antibody; control of antibody affinity and heterogeneity; ontology of hetero- geneity of antibody affinity; effect of aging on the immune response K. H. Stenzel: Proliferation and differentiation of immu- nocompetent cells D. H. Sussdorl: Immunological factors in carcino- genesis; immunocompetence of the athymic ('nude') mouse; macrophage function M. E. Weksler: Lymphocyte interactions with autolo- gous cells in autoimmune and neoplastic diseases; immunobiology of aging M. E. Wiebe: Human interferon induction, synthesis and regulation; molecular virology Courses Students who want to attend any of the following courses either for credit or as auditors should contact the Field Director or the faculty member responsible for each course well in advance of the beginning of each course. In general, as many students as possi- ble are accommodated in lectures; however, participation in laboratory sections is restricted. 1. Microbiology and an Introduction to Infectious Disease Presented in the first and second trimes- ters. Consists of laboratory experiments, lectures, and group discussions. The laboratory work includes an introduction to the procedures used in studying micro- organisms, experiments on various physical and biological manifestations of antigen-antibody reac- tions, the actions of chemotherapeutic agents, a survey of the microbial flora of the upper respiratory and lower intestinal tracts of healthy humans, and an intensive study of the causal agents of specific infec- tions, including fungi, spirochetes, rickettsiae, and viruses, as well as bacteria. The lectures are directed toward the development of basic concepts, particularly the principles involved in microbial growth, the princi- ples underlying active immunization, and the factors that enter into host-parasite relationships. Emphasis is placed on aspects related to the etiology, patho- genesis, epidemiology, and prevention of infectious aisease Special attention is also given to the immu- nological principles underlying such noninfectious conditions as hypersensitivity, autoimmunity, and graft rejection Offered every year. Microbiology staff and invited lecturers. 2. Advanced Diagnostic Microbiology The lecture and laboratory sessions acquaint the student with the procedures used in and techniques of management of a clinical microbiology laboratory. Emphasis is upon developing the student's capability in the isolation and rapid identification of organisms from various types of clinical specimens Liberal use is made of clinical materials available through the diagnostic laboratories of the New York Hospital Offered every year in the third trimester Hours by arrangement L. B Senterfit 3. Microbial Chemistry and Physiology Lectures cover literature and methodology pertinent to phys- icochemical properties of microorganisms and their environments, the growth and death of microorgan- isms, chemical composition of cells and subcellular structures, nutritional requirements, microbiological assay and auxotrophic mutants, energy metabolism, degradations and biosyntheses, the physiology of pathogenesis, and important microbial products. Lab- oratory sessions provide experience with large-scale culture and recovery of cells, synthetic media, micro- biological assay, extraction of cellular constituents, respirometry, and studies of substrate utilization em- ploying radioactive metabolites. Minimal prerequisites: general microbiology, qualitative and quantitative analysis, organic chemistry, and at least one semester (or its equivalent) of biochemistry. Not offered in 1983-84. 4. Advanced Virology Presents, in lectures and lab- oratory sessions, modern concepts and techniques of virology. Minimal prerequisites for credit are general microbiology and at least one semester (or its equiv- alent) of biochemistry. Not offered in 1983-84. 5. Research on Special Problems For students who want significant experience in specialized pro- cedures, which they could not obtain otherwise, the Field offers individualized research on special prob- lems. The nature, complexity, and time required for such research vary according to the needs and de- sires of each student. Such experience is available in each specialty covered by the faculty of the Field and can be arranged by consultation of the student with the appropriate faculty member. Available each year and throughout the year. The staff. 6. Thesis Research in Microbiology Required of all students taking a major in microbiology. Offered yearly and throughout the year. The staff. 7. Microbiology Seminar Reports on surveys of the literature in the field and on current research. Pre- sented by graduate students, faculty, and visiting scientists. Attendance is required of all students ma- joring or minoring in microbiology throughout their programs of study. Offered yearly and throughout the year. One-hour sessions alternate weeks, hours to be arranged. L. Senterfit. 8. Clinical Microbiology Program— Ithaca and New York Campuses During the senior year of a special undergraduate study program at Ithaca or during the year after receiving a bachelors degree, the student may concentrate on developing skills in clinical micro- biology at the Cornell Medical School-New York Hospital in New York City. Students participate in courses concerned with microbiology, an introduction to infectious diseases, diagnostic microbiology, para- sitology, immunology, and virology, in addition to working in the hospital diagnostic laboratory. This clinical microbiology specialization is designed to pre- pare students for employment in clinical microbiology laboratories However, it could also be selected by students interested in further education or other careers Instruction — Medical College Division 19 Neurobiology and Behavior Faculty H. D. Baker, I. B. Black, D. C. Brooks, A. J. L. Cooper, T. Duffy, D. Gardner, M. S. Gazzaniga, J. G. Gibbs, Jr., G. E. Gibson. B. Grafstein, W. D. Hagamen, K. A. Halmi, M. Hamburg, T. H. Joh, B. B Kaplan, D. Levy, K. W. Lieberman, H. M. Moon, M. Okamoto, V. M. Pickel, F. Plum. D. J. Reis, W. F. Riker, Jr., D. A. Rottenberg. J. A. Sechzer, G. P. Smith, P. E. Stokes, G. Teitelman Field Director T. H. Joh, Department of Neurology, Kips Bay Build- ing. Medical College, (212) 472-5594 Faculty Representative G. E. Gibson, Department of Neurology, Burke Re- habilitation Center. White Plains, NY, (914) 948-0050, Ext. 2291 The Field of Neurobiology and Behavior provides training in the study of the nervous system. It includes the disciplines of neuroanatomy, neuroembryology, neurophysiology, neuropharmacology, neurochemistry, neuroendocrinology, molecular biology, and neuropsy- chology and perception. The program of the Field emphasizes a multi-disciplinary approach to the study of the nervous system, based on the belief that future advances in our understanding of the nervous system will be derived from knowledge of the thinking and research techniques employed by more than one dis- cipline. Toward this end, the program of the students entering the Field is planned in consultation with sev- eral staff members, and the students are expected to spend some period c*' time working closely with mem- bers of the faculty whose interests are related to theirs. In addition, there are regularly scheduled semi- nars in the Field during which various aspects of work in progress are presented and discussed. By these means, the students are afforded the broadest possi- ble view of the Field during their total training experience. The student majoring in Neurobiology and Behavior will be required to satisfy the requirements of the courses in neuroscience, statistics, and biomathe- matics, and two of the following: Microscopic anatomy, physiology, biochemistry, and pharmacology. The stu- dent must also have two minors, at least one of which is outside the Field. In addition, participation in the seminar program and advanced course offerings is expected. While there are no language requirements, it is suggested that the student achieve mastery of a modern foreign language or a computer programming language. The student choosing Neurobiology and Behavior as a minor is required to participate in the neuroscience course and the seminar program as well as obtain any additional experience that the minor sponsor may suggest. Applicants to the Field are expected to have had ade- quate undergraduate training in biology, organic chemistry, physics, and mathematics. Graduate Rec- ord Examination scores are to be submitted with the application. An interview with the applicant is consid- ered highly desirable. Special interests of the Faculty H. D. Baker: Quantitative immunocytochemical analy- sis of enzyme expression I. Black: Biochemistry of neuronal plasticity: growth and development D Brooks: Brain stem influence on the electrical ac- tivity of the visual system during sleep and wakefulness A. J. L. Cooper: Ammonia, amino acid and alpha-keto acid metabolism in the brain: use of positron- emitting isotopes as tracers in biochemistry T. E. Duffy: Neurochemistry; carbohydrate and energy metabolism in altered functional states of the brain; cerebral ammonia detoxification and hepatic coma; metabolic dysfunction in the perinatal brain D. Gardner: Neurobiology and biophysics of inverte- brate synaptic transmission M. S. Gazzaniga: Neuropsychological approaches to behavior J. Gibbs: Neuroendocrine mechanisms of motivated behavior, especially feeding behavior G. E. Gibson: Relationship of oxidative and calcium metabolism to neurotransmitter interactions B. Grafstein: Growth of nerves and the transport of materials in axons W. D. Hagamen: Computer models of learning behavior K. A. Halmi: Endocrine investigations; epidemio- logical-demographic treatment studies of eating disorders M. D. Hamburg: Regulatory mechanisms for the bio synthesis of catecholamine neurotransmitters T. H. Joh: Gene regulation and control mechanisms of neurotransmitter enzymes B. B. Kaplan: Gene activity and its regulation in brain and cultured cells of neuroectodermal origin D. E. Levy: Mechanisms of ischemic brain damage; database analysis of natural clinical history of se- vere metabolic brain disease K. W Lieberman: Neurochemical aspects of mental illness and alcoholism H. M. Moon: Molecular biology of human chromosome 21 (q221 and q222) M. Okamoto: Neuropharmacology; sedative-hypnotic drug dependence V. M. Pickel: Ultrastructural studies of synaptic interac- tions between monoaminergic and peptidergic neurons in brain F. Plum: Cerebral metabolism in disease states; cen- tral regulation systems D. J. Reis: Neurobiology of central regulation of auto- nomic nervous system; regeneration and degeneration in CNS; neurobiology of central monoamine neurons W. F. Riker, Jr.: Pharmacology and physiology of neu- romuscular transmission D. A. Rottenberg: Positron emission tomography of the central nervous system; quantitative auto- radiographic measurements of regional cerebral metabolism J. Sechzer: Neurobehavioral toxicology; learning and memory in split-brain animals, early development G. Smith: Feeding behavior, emotional behavior, and learning in rats and monkeys, utilizing concepts of neuroendocrinology 20 Instruction — Medical College Division P. Stokes: Neuroendocrine and biogenic amines in their relationship to behavior with special attention to depression G. N. Teitelman: Factors affecting differentiation of neurotransmitter biosynthetic enzymes in the au- tonomic nervous system Courses 1. Neuroscience This is the basic undergraduate medical course and is required of all major and minor candidates in the Field. It is a broadly based course taught by members of the Field and introduces the student to neuroanatomy, neurophysiology, and perti- nent neurology. Third trimester. D. Brooks and B. Graf stein. 2. Advanced Neurobiology Seminar An elective seminar series covering selected topics in neurophar- macology, neurochemistry and neurophysiology. Offered in the first and second trimesters, one hour each week. F. Plum and staff. Pathology Faculty D. R. Alonso, C. G. Becker, P. G. Bullough, J. T. Ellis, D. Hajjar, A. Kellner, R. C. Mellors, C. R. Minick, G. E. Murphy, C. K. Petito, M. J. Polley, A. M. Prince, C. A. Santos-Buch, L. B. Senterfit, M. E. Weksler Field Director J. T. Ellis, Department of Pathology, Room C-314, Medical College, (212) 472-5940 Faculty Representative C. G. Becker, Department of Pathology, Room C-444, Medical College, (212) 472-5983 Pathology is the study of the causes and mechanisms of disease processes. The purpose of a graduate program in pathology is to provide individuals with a baccalaureate or medical degree with basic knowl- edge of disease processes through study of the disciplines of anatomic and clinical pathology and by learning modern techniques of biological investigation. It is hoped that a student completing this program will have both the information and technical skills to make significant inquiries into the nature of disease proc- esses and to bridge the gap between classical, descriptive pathology and such disciplines as bio- chemistry and molecular biology. The graduate program in pathology includes the ob- servation of diseases in their various forms at autopsy and in clinical laboratories and study and research in the areas of immunology and immunopathology, on- cology, virology, cellular biology, and electron microscopy. It may also include study in advanced mathematics, physiology, biophysics, pharmacology, anatomy, cytochemistry and histochemistry, advanced biochemistry, genetics and microbiology. New students are required to have completed mathe- matics through integral calculus, chemistry through organic chemistry (although physical chemistry is rec- ommended), basic physics and at least general biology A reading knowledge of at least one foreign language is suggested but not required. For those students entering the program with baccalaureate de- grees only, the Graduate Record Examinations, including the Aptitude Tests and the Advanced Test in biology or chemistry, are required. Graduate students in pathology are required, as a beginning part of their program, to take the course in general and systemic pathology offered to second- year medical students. They must minor in at least one and not more than two other biomedical fields. Courses in biomathematics, biochemistry, genetics, and microbiology are also required. Additional courses not available at the Graduate School of Medical Sci- ences can be taken at neighboring institutions with approval of the Field of Pathology and the candidate's Special Committee. Special Interests of the Faculty D. R. Alonso: Cardiovascular pathology C. G. Becker: Cardiovascular and renal diseases; im- munopathology; host-parasite relationships P. G. Bullough: Diseases and metabolism of bone J. T. Ellis: Electron microscopy; kidney disease; mus- cle diseases D. Hajjar: Pathology of atherosclerosis A. Kellner: Immunohematology; lipid metabolism; pathogenesis of arteriosclerosis R. C. Mellors: Studies in immunopathology relating to the role of viruses in autoimmune disease and leukemogenesis C.R. Minick: Pathogenesis of arteriosclerosis and hy- pertension; lipid metabolism; immunopathology; electron microscopy G. E. Murphy: Cardiovascular diseases; host-parasite relationships C. K. Petito: Neuropathology; ultrastructure and histo- chemistry of diseases of central nervous system M. T. Polley: Biology of complement in platelet physiol- ogy; immunoelectronmicroscopy A. M. Prince: Virology; pathogenesis of liver diseases C. A. Santos-Buch: Cellular biology; immunopathol- ogy; cardiovascular disease; electron microscopy L. B. Senterfit: Antigenic structure of mycoplasma; pathogenesis of respiratory viral and mycoplasmic disease; vaccine development; clinical microbiology M. E. Weksler: Lymphocyte interactions with autolo- gous cells in autoimmune and neoplastic diseases; immunology in aging Courses 1. General and Systemic Pathology Lectures, practical classes, and seminars. First trimester: M W F 9-1, Tu 10-12. Second trimester: M W 10-1, F 9-1. The staff. 2. Correlative Pathology Gross and microscopic material is correlated and related to the disease proc- esses. The staff. 3. Forensic Pathology Courses are offered by spe- cial arrangement with the chief medical examiner of New York City. 4. Seminars in Pathology Discussions outlining the scope of modern pathology are given weekly. These include reports on original research by members of the staff and by visiting lecturers. Hours to be ar- ranged. The staff. Instruction— Medical College Division 21 5. Experimental Pathology Independent research projects in various areas of pathology are offered. The staff. Related Courses The following courses are offered by various members of the Field in collaboration with faculty members of related fields. The terms and hours are by arrangement. Immunopathology Cardiovascular Pathology Autopsy Pathology Orthopedic Pathology Renal Pathology Gastrointestinal Pathology Neuropathology Surgical Pathology Cytopathology Tumor Pathology Clinical Biochemistry Hematology and immunochematology Clinical Microbiology Pharmacology Faculty W. W. Y. Chan, D. F. Felsen, O. W. Griffith, W. Houde, C. E. Inturrisi, B. Jones, R. F. Kaiko, R. Levi, M. Okamoto, G. W. Pasternak, M. M. Reidenberg, A. Rifkind, W. F. Riker, Jr., H. H. Szeto Field Director W. W. Y. Chan, Department of Pharmacology, Room E-417, Medical College, (212) 472-5969 Faculty Representative M. Okamoto, Department of Pharmacology, Room E-411, Medical College, (212) 472-5975 The graduate program emphasizes sound basic train- ing in general pharmacology. Then, by means of individual instruction, the candidate receives exposure to several specialized aspects of pharmacology. The latter part of the graduate curriculum is devoted to research in an area of the candidate's choice. An adequate preliminary training in organic chemistry, physical chemistry, biochemistry, and physiology is prerequisite to graduate work in pharmacology. Train- ing in statistics is strongly recommended. Special Interests of the Faculty W. W. Y. Chan: Renal pharmacology; endocrine phar- macology, polypeptide pharmacology D. F. Felsen: Prostaglandin pharmacology; hypertension O. W. Griffith: Biochemical pharmacology; design and synthesis of enzyme specific substrate and inhibi- tor; in vivo manipulation of metabolic pathways R. W. Houde: Clinical pharmacology of the analgesic drugs; development of methods of evaluating the effects of drugs on subjective response C. E. Inturrisi: Biochemical pharmacology; narcotic drug metabolisms and responses B. Jones: Clinical pharmacology, chemotherapy of neoplastic diseases R. F Kaiko: Clinical pharmacology of analgesic drugs R. Levi: Cardiovascular pharmacology; immuno- pharmacology; anaphylactic responses of car- diovascular system M, Okamoto: Neuropharmacology; sedative-hypnotic drug dependence G. W. Pasternak: Molecular pharmacology, narcotic drug receptors M. M. Reidenberg: Clinical pharmacology; drug metabolism A. Rifkind: Clinical pharmacology; biochemical phar- macology and toxicology, development of drug- metabolizing enzymes W. F. Riker, Jr.: General pharmacology; neurophar- macology; neuromuscular transmission H. H. Szeto: Fetal pharmacology and physiology; drug transfer and metabolism in the fetus Courses I. General Pharmacology The basic pharmacology course is offered to second-year medical students and to qualified graduate students. It consists of lectures laboratory work, demonstrations, and seminars give during the first and second trimesters. The purpose of these exercises is to teach the principles of phar- macology. Detailed consideration is given to the parameters of drug action to provide the student with the fundamental concepts essential for the evaluation of any drug. Consequently, the scientific basis of phar- macology is emphasized. Prototype drugs, essentially considered systemically, serve to illustrate several mechanisms and parameters of drug action. Therapeutic applications are considered only insofar as they illustrate principles of pharmacology or drug hazards. Prerequisites: biochemistry and physiology The staff. 2. Advanced Courses in Pharmacology a. Molecular Pharmacology Fundamental princi- ples governing the effects of chemicals on living systems are examined from the viewpoint of drug- receptor interactions. Several concepts are introduced including drug selectivity, specificity dose-response, and receptor theory. Examples of receptor isolation and receptor-drug interactions are discussed in detail. Prerequisites: An adequate background in biology, organic and physical chemistry, and biochemistry is required. The staff and invited lecturers. Offered every other year. b. Immunopharmacology The course focuses on the fundamentals of immunologic cell reactions and explores the mechanism of therapeutic immunologic regulation. Topics include: inflammatory and allergic processes; mechanism of cell activation; mediated re- lease and action; cyclicnycleotides and prostaglan- dins; lymphokines, interferons and thymic hormones; immunotoxicology; immunologic assays and use of biologies and drugs for immunotherapy A background 22 Instruction — Medical College Division in immunology would be helpful but not required. The course is offered by the joint efforts of the faculties of the Medical College and the Sloan-Kettering Divi- sions, and is offered every other year. 3. Research in Pharmacology Research oppor- tunities may be arranged throughout the year for graduate students who are not majoring in pharmacol- ogy but who want some investigative experience in the discipline. Special opportunities are offered for work on the nervous and cardiovascular systems and in biochemical and clinical aspects of pharmacology. The staff. 4. Seminars The Field of Pharmacology offers semi- nars in areas of interest to the faculty and graduate students of the field. Seminars in clinical pharmacol- ogy and teaching rounds are held regularly throughout the year. The content, format and schedule of these seminars are determined each year on the basis of the number and the backgrounds of the interested stu- dents. The staff. Physiology and Biophysics Faculty O. S. Andersen, W. A. Briscoe, W. W. Y. Chan, C. Fell, G. Frindt, D. Gardner, B. Grafstein, Roger L. Greif, E. Heinz, L. E. Hinckle, Jr., N. B. Javitt, C. Lee, R. Levi, M. Lipkin, T. Maack, L. Palmer, T. G. Pickering, E. M. Rabellino, H. J. Sackin, A. M. Weinstein, E. E. Windhager Field Director E. E. Windhager, Department of Physiology and Bi- ophysics, Room C-508, Medical College, (212) 472-5229 Faculty Representative T. Maack, Department of Physiology and Biophysics, Room D-407, Medical College, (212) 472-5281 Opportunities are offered toward the Ph.D. degree in several areas of physiology and biophysics. Ample space is available, and laboratories are well equipped to provide predoctoral training in a medical environ- ment. Interested individuals are urged to contact the Field Director before preparing a formal application. Letters of inquiry should include a discussion of the educational background and indicate possible areas of emphasis in graduate study. There has been a tend- ency to encourage applications from individuals who have a probable interest in one or more of the areas of physiology represented within the field. Formal applications should include full college tran- scripts and at least two letters of recommendation. Graduate Record Examination scores are mandatory, since performance in these examinations is an impor- tant factor in the selection of applicants. Introductory courses in biology, inorganic and organic chemistry, physics, and mathematics through the level of differen- tial and integral calculus are required. Additional course work in these disciplines at the undergraduate level is encouraged Applicants with otherwise exem- plary records who lack certain course requirements will be considered for acceptance provided that they remedy their deficiencies while in training. The course of study emphasizes the importance of teaching and research in the preparation and develop- ment of individuals for careers in physiology. This goal is achieved by a combination of didactic courses, sem- inars, and closely supervised research leading toward the preparation of a satisfactory thesis. A special program of study will be developed for each student in consultation with his or her Special Com- mittee. In addition to the general requirements set by the Graduate School for all fields, all candidates for the doctoral degree in physiology will be expected to meet the following requirements: 1 . Evidence of a satisfactory background in neuro- sciences. Ordinarily, the course in neuroscience described under the Field of Neurobiology and Be- havior, or an equivalent course, will be taken concurrently with the course in physiology and biophysics. 2. Satisfactory completion of the course in physiology and biophysics, or an equivalent course. 3. For majors and minors in the Field, a minimum of two elective courses in the Field ordinarily will be required, in addition to the course in physiology and biophysics. 4. Proficiency in reading scientific literature in one modern foreign language. 5. Satisfactory completion of an individualized labora- tory experience in an area of research different from that chosen for the doctoral dissertation. Special Interests of the Faculty O. S. Andersen: Properties of cell membranes, artifi- cial lipid membranes W. A. Briscoe: Blood gas transfer in health and disease W. W. Y. Chan: Pharmacology of neurohypophyseal hormones and related polypeptides C. Fell: Cardiovascular function, particularly blood flow distribution, blood volume, and blood volume distribution G. Frindt: Renal electrolyte metabolism; isolated per- fused tubules D. Gardner: Neurophysiology B. Grafstein: Nerve regeneration and transport of ma- terial in nerve axons E. Heinz: Membrane transport; active transport L. E. Hinckle, Jr.: Epidemiology and pathophysiology of cardiac arrythmias and the relationship to sudden death N. B. Javitt: Gastrointestinal and hepatic physiology and pathophysiology C. Lee: Cardiac electrolyte physiology R. Levi: Heart electrophysiology; heart hypersen- sitivity reactions; histamine in cardiac function M. Lipkin: Proliferation and differentiation of normal and diseased gastrointestinal cells T. Maack: Protein transport and metabolism by the kidney L. Palmer: Mechanisms of hormonal action in epithelia T. G. Pickering: Cardiovascular physiology and pathophysiology E M. Rabellino: Expression of membrane receptors and antigens in differentiating blood cells H. J. Sackin: Renal and epithelial electrophysiology Instruction — Sloan-Kettering Division 23 A. M. Weinstein: Mathematical modeling of epithelial transport E. Windhager: Renal electrolyte metabolism Courses Students who plan to register for the course Physiol- ogy and Biophysics must consult the Field Director before the start of the second trimester. Students who want to take any of the third-trimester courses (num- bered 2-7) are advised to consult the Field Director no later than the seventh week of the second trimester in order to assure a place in the course. 1. Physiology and Biophysics Lectures and con- ferences in body fluids, bioelectric phenomena, circulation, respiration, and gastrointestinal function. Second trimester, four hours each week. The staff. Lectures and conferences on kidney function, acid- base regulation, endocrinology, and metabolism; and a weekly laboratory on selected aspects of physiology. Third trimester, eleven hours each week. The staff. 2. Respiratory and Renal Mechanisms of Regula- tion of Acid-Base Balance Each session consists of an informal lecture and a succeeding seminar dis- cussion based on assigned reading in the area of the lecture. Third trimester, three hours each week. Five to fifteen students. 3. Selected Topics in Endocrinology important scientific papers dealing with certain aspects of endo- crinology are distributed to the participants one week in advance of discussion. Each paper is considered in detail in a seminar directed by an investigator in the area under discussion. One or two preliminary orienta- tion sessions are o-ven by Professor Greif before distribution of the first scientific paper, and, if feasible, one or two laboratory days are planned. Third trimes- ter, three hours each week. Six to twelve students. Staff. 4. Selected Topics in Gastrointestinal and Hepatic Physiology and Pathophysiology Topics include bilirubin metabolism and excretion, cholesterol metab- olism, bile salt excretion, bile formation, esophageal motility, gastric function, intestinal cell turnover, ab- sorption of fat, absorption of carbohydrate, the malabsorption syndrome. Third trimester, two hours each week. Six to twelve students. N. B. Javitt. 5. Selected Topics in Respiratory Physiology Topics covered include: (1) physiological anatomy of the lung; (2) logical formulation and solution of clinical problems; (3) ventilation, alveolar air diagram, nitro- gen washout; (4) relevant lung function tests; (5) lung volumes, effect of posture and disease; (6) diffusion, Fick equation, Bohr integration; (7) acid-base consid- erations in blood; (8) mechanical properties of lung; (9) ventilation-perfusion ratio and Bohr integral iso- pleths; (10) ecology, sealed spaces, altitude, diving; (11) lung function in the first week of life. Students who want to take this course must consult Professor Bris- coe no later than the seventh week of the second trimester. Third trimester, two hours each week. Max- imum of twelve students. W. A. Briscoe. 6. Selected Topics in Kidney and Electrolyte Phys- iology and Pathophysiology Lectures, seminars, and demonstrations. Topics include: (1) GFR, clear- ance concept, reabsorption and secretion of electrolytes; (2) concentrating mechanism; (3) elec- trophysiology of the nephron; (4) pathophysiology of potassium; (5) renal blood flow and its mtrarenal dis- tribution; (6) renal physiology in the newborn; (7) control of body fluid volume and tonicity; (8) pathology of renal failure; urinary sediment; pathophysiology of renal failure; (9) radiology of the kidneys; (10) dialysis; (11) transplantation. Third trimester, two hours each week. Maximum of twelve students. E. Windhager and staff. 7. Special Topics in Cardiovascular Physiology Original research papers will be made available in advance of each session, and these and the general problems associated with each topic will serve as the basis for the discussion. Insofar as possible, experi- mental approaches to each problem will be demonstrated. To some extent, choice of topics can be determined by the interests of the group. Probable topics include: (1) regulation of peripheral blood flow; (2) integrated cardiovascular responses to hypoxia; (3) pulsatile flow in arteries; (4) measures of myocar- dial performance; (5) blood volume, hemorrhage, and hemorrhagic shock; (6) cardiac catheterization in man, congenital heart disease, valvular heart disease. Third trimester, three hours each week. Six to twelve stu- dents. C. Fell. Instruction at the Sloan-Kettering Division 1. Graduate Seminar This weekly graduate seminar is offered each year. During the first trimester, second- year students will present brief reports on their re- search experiences in the laboratory rotations. First year students may report on laboratory rotations, re- view a selected area of research or critically review a research paper. The discussion is carried out prin- cipally by graduate students under the guidance of their major (temporary or permanent) sponsors. From time to time outstanding authorities are invited as guest speakers. In addition, students in their third and later years of graduate study, address the seminars on the progress being made in their thesis work. 2. Laboratory Rotations Throughout the year stu- dents should spend time in research laboratories. Arrangements for laboratory rotation should be made with the major sponsor. 3. Minor Projects Two minor subjects are required of all students and they include some laboratory train- ing, i.e., a minor project. The major sponsor assumes the responsibility for monitoring the time spent on the project. Minor subjects should be completed before the Admission to Candidacy Examination. 4. Laboratory Safety and Biohazards Course All students are required to take by their second year the course of six basic lectures sponsored by the Sloan- Kettering Institute Institutional Biosafety Committee The series covers general laboratory safety, the use of radioisotopes, carcinogens, primary and secondary barrier systems, contamination control, and hazards associated with research animals, and is supple- 24 Fees and Expenses merited by lectures on special topics given throughout the year. Cell Biology and Genetics Faculty K. Artzt, M. E. Balis, D. Bennett, J. L. Biedler, R. S. Bockman, E. Borenfreund, R. S. Chaganti, Z. Darzynkiewicz, E. E. Deschner, D. B. Donner, M. Eisinger, J. E. Fogh, E. A. Friedman, J. A. Gurr, P. J. Higgins, D. J. Hutchison, L. Kopelovich, I. A. Kourides, R A. Marks, M. R. Melamed, M. B. Meyers, A. C. Moore, M. A. S. Moore, P. M. Ralph, R. A. Rifkind, A. S. Schneider, M. R. Sherman, A. E. Silverstone, M. Siniscalco, M. Sonenberg, P. Szabo, L. C. Yip, M. S. Zedeck Program Chairman J. L. Biedler, Sloan-Kettering Institute, Walker Labora- tory, Room 2127, (914) 698-1100, Ext. 243 Unit Chairman D. B. Donner, Sloan-Kettering Division, Howard Labo- ratory, Room 909, (212) 794-7871 The program deals with aspects of developmental cell biology including embryogenesis, growth and differen- tiation of normal and transformed cells, endocrinology and hormone receptors, as well as genetics, cytogenetics and somatic cell genetics. Students will spend their first year in: 1) satisfying course and seminar requirements; 2) participating in laboratory rotations; and 3) initiating one or two minor projects. The Unit Chairman will serve as temporary major advisor during this time. At the end of the first year the student's performance will be reviewed and a Special Committee of three members will be selected. The Special Committee membership must provide multidisciplinary academic backgrounds. During the second academic year students should complete two minor projects, satisfy the requirements of the Admission to Candidacy Examination and initi- ate a thesis project. Prerequisites for a major in Cell Biology include courses in chemistry (through organic), biochemistry, physics, mathematics (through calculus) and general biological sciences (botany, zoology, microbiology, cell biology); physical chemistry is recommended. Submission of Graduate Record Examination results, in both aptitude (verbal and quantitative) and the ad- vanced test in biology or chemistry is required. Programs will be determined individually on the basis of interest and prior experience. Students are ex- pected to have knowledge of materials offered in the Instruction — Sloan-Ketterlng Division 25 courses of the Unit and microscopic anatomy. Exemp- tion from the courses can be granted following the successful completion of a written examination. Stu- dents majoring in cell biology may be advised to register for courses in molecular biology, genetics, biochemistry and biostatistics. Special Interests of the Faculty K. Artzt: Cell surfaces and tumorigenesis M. E. Balis: Enzymology and metabolism of trans- formed cells D. Bennett: Developmental genetics and differentiation J. L. Biedler: Cytogenetics and gene amplification R. S. Bockman: Hypercalcemia and carcinogenesis E. Borenfreund: Environmental toxicology R. S. Chaganti: Cytogenetics Z. Darzynkiewicz: Cell metabolism in differentiation E. E. Deschner: Cell proliferation and differentiation D. B. Donner: Hormone receptor structure and function M. Eisinger: Cell growth and differentiation J. E. Fogh: Cancer cell biology and virology E. A. Friedman: Cell growth and differentiation J. A. Gurr: Regulation of thyrotropin gene expression P. J. Higgins: Gene organization and differentiation D. J. Hutchison: Drug resistance and cytoregulation L. Kopelovich: Neoplastic transformation I. A. Kourides: Regulation of thyrotropin and gonadotropins P. A. Marks: Developmental cell biology M. R. Melamed: Tumor cell cytology M. B. Meyers: Biochemical genetics A. C. Moore: Membrane structure and function M. A. S. Moore: Hemapoietic cell differentiation P. M. Ralph: Regulation of macrophage cytotoxicity; cell differentiation R. A. Rifkind: Cell growth and differentiation A. S. Schneider: Cell surface receptor regulation M. R. Sherman: Steroid hormone action A. E. Silverstone: Chemical carcinogenesis M. Siniscalco: Human genetics and cytogenetics M. Sonenberg: Endocrinology and hormone receptor biology P. Szabo: Genome organization; viral and host ge- nome interaction L. C. Yip: Enzymes in purine metabolism, aging, carcinogenesis M. S. Zedeck: Mechanisms of chemical carcinogenesis Courses 1. Tutorial in Cell Biology and Biochemistry A course designed to familiarize graduate students with fundamental concepts of cell biology and biochemis- try Topics will include cell structure, organization and function, intermediary metabolism, and molecular bio- chemistry. Hours will be arranged between small groups of students and faculty tutors. Offered first trimester each year. M. Eisinger and staff. 2. Topics in Cell Biology Staff and invited lecturers will discuss the latest research in cell structure and function. Topics will include cellular organization, cell- cell recognition, cell growth and division (particularly contrasting normal and neoplastic development), dif- ferentiation, cell movement and genetics and gametogenesis. The format will include a weekly 2-3 hour meeting with required reading of current scientific papers and student analysis of these papers Offered 2nd and 3rd trimester 1983-84. A E. Silverstone and staff. 3. Hormone and Neurotransmitter Receptors This course presents the fundamentals of hormone-and neurotransmitter-dependent cell regulatory mecha- nisms. Topics include: peptide hormone and neurotransmitter action at cell surface receptors; mechanisms of secretion of hormones and neu- rotransmitters. Second trimester. M. R. Sherman and staff. Not offered in 1983-84. 4. Endocrine Research in Progress Seminars Re- ports of on-going research by faculty of the Graduate School of Medical Sciences, Cornell University Medi- cal College and Rockefeller University, are given weekly. 5. Advanced Genetics Designed to give the student a sound background in genetic theory; an in-depth consideration of the gene as a unit of heredity. D. Bennett and staff. 6. Flow Cytometry This brief tutorial will include lectures and demonstrations on the principles of cell measurements and sorting as they are applied to basic cell biology, with special emphasis on nucleic acid content, cell cycle analysis, differentiation and transformation. Z. Darzynkiewicz and staff. 7. Cell Culture Tutorial Short term courses in tissue culture techniques will be offered to a limited number of students in laboratories of cell biology unit mem- bers. Sessions can count as lab rotations or be expanded into minor projects. J. L. Biedler and staff. 8. Cellular Differentiation Journal Club A weekly informal discussion of recent publications or research of common interest in cell biology and differentiation. Participants are responsible for choosing a presenta- tion for the week. E. A. Friedman and staff. Developmental Therapy & Clinical Investigation Faculty N. W. Alcock, L. L. Anderson, J. R. Bading, R. E. Bigler, T. -C. Chou, A. M. Dnistnan, A. M. Feinberg, M. Fleisher, J. Fried, J. J. Fox, A. S. Gelbard. N. L. Geller, M. C. Graham. S. Groshen, Y. Hirshaut, J. H. Kim, J. S. Laughlin, B. M. Mehta, V. Mike, J. S. Nisselbaum, B. A. Otter. F. S. Philips, J. Roberts. B. Schmall. M. K. Schwartz, F. M. Sirotnak, P. P. Sordillo. S. S. Sternberg, H. T. Thaler, K. A. Watanabe, H. Weiss. L Zeitz Acting Program Co-Chairman J J. Fox, Sloan-Kettering Institute, Walker Laboratory, Room 3037. (914) 698-1100. Ext. 225 Unit Chairman F. M. Sirotnak. Sloan-Kettenng Division, Kettering Laboratory. Room 316. (212) 794-7952 In this multidisciplinary program, opportunities for ad- vanced study are focused on laboratory, clinical and or 26 Instruction — Sloan-Kettering Division statistical research as they relate to cancer prevention, diagnosis and treatment. Undergraduate prerequisites vary with the subspecialty area of training in which the student wishes to concentrate; the areas of study offered and their recommended undergraduate back- grounds are reviewed briefly below. Graduate Record Examination results in both the apti- tude test (verbal and quantitative) and the advanced test in an appropriate area of concentration are re- quired to be submitted by all students of the Unit. Once accepted, students must complete requirements established by the Division including a dissertation under the direction of the Student's Special Committee. 1. instruction toward the Ph.D. degree with empha- sis in Biochemical and Molecular Pharmacology, Medicinal Chemistry and Biochemistry, Clinical Chemistry and Biochemistry, Cancer Therapeutics and Toxicology. Undergraduate majors in biology, chemistry or health sciences are most appropriate backgrounds for admis- sion. In addition, students should have adequate training in organic chemistry, physical chemistry, bio- chemistry and physiology. Training in statistics is recommended. Course requirements include advanced instruction in cell and molecular biology, and courses appropriate to the subspecialty pursued by the student. Other courses might include one or more of the following: Advanced biochemistry microscopic anatomy, physiol- ogy, neurosciences, biostatistics and both general and advanced pharmacology. The program of study de- signed for each student will, in general, reflect the level of the student's undergraduate preparation. Special Interests of the Faculty N. W. Alcock: Trace metals, parenteral nutrition T.-C. Chou: Molecular pharmacology and enzymology A. M. Dnistrian: Membrane composition and carcinogenesis A. M. Feinberg: Pharmacology and analytical biochemistry M. Fleisher: Tumor associated antigens; clinical chem- ical automation J. J. Fox: Organic synthesis and drug development Y. Hirshaut: Human tumor antigens B. M. Mehta: Quantitative microbiology, pharmacokinetics J. S. Nisselbaum: Enzyme activity; isozymes B. A. Otter: Antitumor agent synthesis F. S. Philips: Pharmacology of antitumor and car- cinogenic agents J. Roberts: Antitumor enzymes and nutritional depriva- tion of neoplasmas M. K. Schwartz:Clinical biochemistry F. M. Sirotnak: Molecular pharmacology and mem- brane transport S. S. Sternberg: Pathology of drug action K A. Watanabe: Medicinal chemistry and biochemistry 2. Instruction toward the Ph.D. degree with em- phasis in Radiation Biology, Radiation Physics and Radiopharmaceutics. Applicants should have a major in biophysics or a major in biology, chemistry or mathematics with train- ing in general physics, electricity and magnetism, mechanics, mathematics (through calculus) and thermodynamics. Students will be required to take advanced instruction in cell and molecular biology, and in physics, bio- chemistry and mathematics, depending upon the level of prior training. Instruction toward the M.S. degree in Radiation Phys- ics is also offered for candidates holding a B.A. or B.S. in physics. These candidates are expected to take advanced instruction in physics, biophysics, biology, radiobiology, biochemistry, and biomathematics with a minor in one of these subjects other than physics, and prepare a thesis in the field of radiation physics. The candidates for the M.S. degree must demonstrate a thorough knowledge of this area in a final written and oral examination. Special Interests of the Faculty L. L. Anderson: Radiation dosimetry J. R. Bading: Quantitative imaging R. E. Bigler: Neutron activation in vivo J. Fried: Cytotoxic agents; flow cytofluorometry A. S. Gelbard: Enzymatic synthesis with short-lived isotopes M. E. Graham: Applications of digital image enhancement J. H. Kim: Hyperthermia, radiation and drug actions in cell systems J. S. Laughlin: Radiation biophysics B. Schmall: Synthesis of radiopharmaceuticals P. P. Sordillo: Short-lived radionuclides; diagnosis and treatment of cancer H. Weiss: Fast time processes in biophysics and radiobiology L. Zeitz: Cell damage and repair 3. Instruction towards the Ph.D. degree in Biostatistics. The program is designed to provide training in statisti- cal theory, methodology and computing, combined with broad experience in data analysis and collabora- tive research with medical investigators. Admission to the program requires a B.S. degree in mathematical statistics, or the equivalent. Courses to be completed by each student will depend upon the level of prior training and individual interests. In addition to basic probability theory and statistical inference, there is special emphasis on the design and analysis of clinical trials and the development of skills in exploratory data analysis. Each student participates in an internship program in statistical consulting and collaborative research. A doctoral dissertation in bio- statistics involves the development of new theory or methodology under the direction of a faculty advisor. Special Interests of the Faculty N. L. Geller: Biostatistics - Probability theory; non- parametric inference; clinical trials S. Groshen: Biostatistics - Survival analysis; log-linear models; statistical inference V. Mike: Biostatistics - Robust inference; epidemiol- ogy; genetics H. T. Thaler: Biostatistics - Applied probability; data analysis; statistical graphics Instruction— Sloan-Kettering Division 27 Courses 1. General Pharmacology (see Field of Pharmacol- ogy, Medical College Division) 2. Advanced Pharmacology (Interdivisional). This course will amplify the general pharmacology course focusing on basic aspects such as drug metabolism, enzyme kinetics, pharmacokinetics, pharmacogene- tics, receptors, chemotherapy, drug resistance, membrane transport, toxicology and clinical pharmacology 3. Molecular Pharmacology (see Field of Phar- macology, Medical College Division). 4. Special Topics in Experimental Pharmacology (Interunit). This course is interdisciplinary and will ex- pand the candidate's training in certain specialized areas such as pharmacologic effects on membrane structure and physiology, radio pharmacology, chemi- cal carcinogenesis and medicinal biochemistry F. M. Sirotnak and staff. 5. Radiological Physics, Lectures and Problems A series of the hourly lectures and assigned problems in applied mathematics, fundamentals of radiation physics, x-ray and radium treatment planning, diag- nostic x-ray principles, radiation protection, and uses of radioactive isotopes. Staff. 6. Radiobiology A semester course in fundamental radiobiology dealing with the effects of radiation on cells, viruses, and macromolecules, as well as on whole animals. The course also covers areas in radia- tion physics and radiation chemistry pertinent to radiobiology. L. Zerz and staff. 7. Advanced Biophysics Laboratory courses in each of the topics of radiation biophysics. Hours by arrangement. Staff. 8. Radiopharmaceutical Chemistry A tutorial course in radiopharmaceutical chemistry is offered to those students majoring or minoring in this subject. Hours by arrangement. B. Schmall and staff. 9. Biophysics Colloquia Reports on research in pro- gress by faculty and outside lecturers. Required for majors in biophysics. Hours by arrangement. Staff. 10. Biostati sties I: Introduction to Statistical Reason- ing It is the aim of this course to help participants gain some insight into the theory underlying a proba- bilistic approach to the treatment of observational or experimental data, and to acquaint them with the most basic techniques of statistical analysis. First trimester. Staff. 11. Biostati sties II: Experimental Design and Curve Fitting Application of concepts introduced in Bio- statistics I to the analysis of scientific data. Topics include statistical design of experiments, analysis of variance, correlation, and linear regression. Second trimester. Staff. 12. Survival Analysis and Clinical Trials Parametric and nonparametric models of survival times, exponen- tial and Weibull distributions; life-table and Kaplan- Meier estimates; design of randomized clinical trials, concomitant variables, stratification, sample size de- termination; 2- and k-sample techniques for censored data; generalized Wilcoxon and log-rank tests, Cox regression. Third trimester. Staff. 13. Biostatistics Workshop Designed to provide experience in the use of modern computing equip- ment and statistical software for the analysis of scientific data. To be taken concurrently with Biostatis- tics I and II. First and second trimesters. Staff. 14. Exploratory Data Analysis Tabular and graphi- cal representation of data; stem-and-leaf diagrams, box plots, multidimensional methods; data reduction; transformations and smoothing; resistant analyses of structured data; diagnostic use of residuals. One tri- mester. Given in alternate years. Immunobiology Faculty J. Abbott, E. A. Boyse, Y. S. Choi, C. Cunningham- Rundles, M. A. B. De Sousa, B. Dupont, R. L. Evans, U. Hammerling, M. K. Hoffmann, G. Incefy, Y. B. Kim, M. E. Kirch, G. C. Koo, E. C. Lattime, G. W. Litman, K. O. Lloyd, C. Lopez, S. Macphail, V. J. Merluzzi, H. F. Oettgen, L. J. Old, R. J. O'Reilly, R. Pahwa, C. D. Platsoucas, M. S. Pollack, B. Safai, M. P. Scheid, F.-W. Shen, 0. Stutman, K. A. Sullivan, J. S. Tung. Program Chairman O Stutman, Sloan-Kettering Institute, Kettering La - ratory, Room 1118, (212) 794-7475. Unit Chairman B. Dupont, Sloan-Kettering Institute, Schwartz Build- ing, Room 711, (212) 794-6005. Opportunities are offered toward the Ph.D. degree in various areas of Immunobiology. These include the disciplines of: immunobiology, immunochemistry, im- munogenetics, immunohematology, immunopathology, immunopharmacology, serology, transplantation im- munology, tumor immunology, immunotherapy, and clinical immunology. Undergraduate prerequisites include a general col- lege-level background in biology and the sciences, including a strong background in genetics, biochemis- try and microbiology. Submission of Graduate Record Examination results, in both aptitude (verbal and quantitative) and the ad- vanced test in biology or chemistry, is required. Programs of graduate study for students majoring in the Immunobiology Unit are determined on an indi- vidual basis. Prior training, experience, and the interests of the student are taken into consideration by the designated Special Committee which oversees the academic development of each student. The first year of study consists of: 1) Completion of course and seminar requirements; 2) participation in laboratory rotations; and 3) initiation of one or two minor projects. During this time, the Unit Chairman serves as a temporary major sponsor. At the e.id of the first year, the student's performance is reviewed At that time a Special Committee is named for each student. The Special Committee consists of three fac- ulty members (one major sponsor or chairman, and 28 Instruction — Sloan-Kettering Division two minor sponsors) from at least two academic disci- plines in the Graduate School of Medical Sciences. Students majoring in Immunobiology are expected to take full advantage of the Unit's core program of courses, which consists, annually, of Introductory Im- munology, Advanced Immunology, Clinical Immunology and Colloquia in Immunology. As appro- priate, students are encouraged to participate in course work in biochemistry, genetics, molecular biol- ogy and biostatistics. Those students lacking sufficient preparation in cell biology and microscopic anatomy may be required to participate in course work in these disciplines. Course work requirements are those set by the stu- dent's Special Committee; participation in the Sloan- Kettering Division Graduate Seminar is required of all students, through the first trimester of their second year. The Unit intends that formal coursework be re- quired to complement, as best possible, the student's previous background and fulfill his or her academic objectives. Formal course work, however, should clearly not interfere with participation in other learning opportunities, such as laboratory rotations, tutorials and minicourses, or seminars and lectures. Students are encouraged to take advantage of the academic opportunities offered by the other Units of the Sloan- Kettering Division, Fields of the Medical College Divi- sion, the Sloan-Kettering Institute, and other nearby institutions. In the second year of study, students are required to take the Admission to Candidacy Examination, before which any minor projects required by the student's Special Committee should be completed. Additionally, students are expected to initiate a thesis project in the second year. Special Interests of the Faculty J. Abbott: Differentiation; cell surface antigens E. A. Boyse: Cell surface immunogenetics Y. S. Choi: Immunocyte differentiation C. Cunningham-Rundles: Immunochemistry of im- mune complexes M. A. B. De Sousa: Immune function control; lympho- cyte circulation B. Dupont: Immunogenetics, transplantation, lympho- cyte regulation R. L. Evans: Immunology of T cells U. Hammerling: Immunogenetics; lymphocyte differentiation M. K. Hoffman: Regulation of humoral immunity G. Incefy: Lymphocyte differentiation; immuno- deficiency Y B. Kim: Immunocyte ontogeny M. E. Kirch: Tumor immunology; regulation of cell growth G. C. Koo: Immunogenetics, surface antigens of lym- phoid cells E. C. Lattime: Cell mediated immunity; lymphokines G W Litman: Immunogenetics; protein structure and function K. O. Lloyd: Immunochemistry; tumor immunology C Lopez: Herpes-virus infections; resistance and chemotherapy S Macphai!: Immunogenetics; T lymphocyte activity V. J. Merluzzi: Antineoplastic agents and cellular immunity H. F. Oettgen: Clinical immunology L. J. Old: Human cancer serology and immunogenetics R. J. O'Reilly: Microbial immunology; transplantation; immunodeficiency R. Pahwa: T cell differentiation C. D. Platsoucas: Regulatory and effector T-cells M. S. Pollack: Immunogenetics; histocompatibility alloantigens B. Safai: T cell lymphomas; epidermal cell differentiation M. P. Scheid: Immunogenetics; lymphocyte development F.-W. Shen: Immunogenetics O. Stutman: Developmental immunology K. A. Sullivan: Lymphocyte subsets; cell-mediated lympholysis J. S. Tung: Immunogenetics Courses I. Introductory Immunology This course is appro- priate for, but not restricted to, students who have had no formal training in Immunology, or who wish to review fundamentals in preparation for the Advanced Immunology course. An overview of specific and non- specific immunity, cellular participants in immune responses, structure of immunoglobulins and cell sur- face receptors, molecular basis of antibody diversity, organization of lymphoid tissues and cell migration, phylogenetic perspectives on vertebrate immunity, specificity to immune responses, methods for measur- ing humoral immune responses, immunogenetics and transplantation immunology, and methods for cell- mediated immune responses are among the topics which will be discussed. First trimester. B. Dupont, U. Hammerling, M. S. Pollack, M. Scheid, O. Stutman, and Staff. 2. Advanced Immunology Lectures, discussions and assigned readings for in-depth studies to cover properties of antigens and antibodies; mechanism of antibody formation; phylogeny and ontogeny of the immune system; structural and functional aspects of the immune system; molecular basis of antibody and lymphocyte diversity; major histocompatibility com- plexes in man and animals; immunogenetics of differentiation; effector mechanisms of antibody and cell-mediated immunity; immunodeficiency diseases; regulation and control of the immune response; genet- ics and immunology of transplants and tumors. Prerequisites for the course are at least one semester or equivalent biochemistry and introductory immunology. Second trimester. B. Dupont, O. Stutman, and Staff. 3. Clinical Immunology Lectures, discussion and assigned readings on subjects related to clinical im- munology, such as histocompatibility antigens; properties of T, B lymphocytes and macrophage cells; lymphoid cell lines; immunopathology; immunodefi- ciencies; immunogenetics; organ and bone marrow transplantation; tumor immunology, etc. Prerequisites are the Introductory Immunology or equivalent course. Third trimester. B Dupont, H. Oettgen, R. J. O'Reilly, and Staff. 4. Colloquia In Immunology Informal sessions be- tween students and senior faculty members. Will take Instruction — Sloan-Kettering Division 29 place second Friday of each month from 4:00-6:00 P.M. The purpose of the colloquia is to acquaint the students with the major research programs headed by each of the senior faculty members of the Immunology Unit. Students from other units are also welcome to these sessions, which will be announced monthly. The colloquia are open to all graduate students indepen- dently of years of study. First Colloquium: Friday, September 9, 1983. B. Dupont, U. Hammerling, M. Pollack, M. Scheid, O. Stutman, and Staff. 5. Laboratory Rotations, Tutorials And Mini- courses In order to become familiar with the various research programs which are available to students doing major or minor work in immunology, the Unit advises entering students to participate in as many laboratory rotations, tutorials and minicourses as can be accommodated into the first-year schedule. The lists and descriptions for laboratory rotations, tutorial programs and minicourses are available from the of- fice of the Unit Chairman. Molecular Biology & Virology Faculty L. H. Augenlicht, I. Balazs, F. 0. Bancroft, P. Besmer, L. F. Cavalieri, S. Y. Chen-Kiang, R. K. Cross, N. G. Famulari, E. Fleissner, S. L. Gupta, W. D. Hardy, Jr., W. S. Hayward, R. M. Krug, P. W. Melera, M. J. Modak, P. V. O'Donnell, A. I. Oliff, A. Pinter, O. Pra- kash, J. V. Ravetch, B. H. Rosenberg, N. H. Sarkar, G. C. Sen, E. Stavnezer, J. M. Stavnezer, G. Stohrer Program Chairman R. M. Krug, Sloan-Kettering Institute, Kettering Labo- ratory, Room 406A, (212) 794-7666. Unit Chairman E. Stavnezer, Sloan-Kettering Division, Kettering Lab- oratory, Room 713, (212) 794-7251. This program includes research on the structure, func- tion and regulation of genetic elements including normal gene expression, oncogenes, oncogenic vi- ruses, and nucleic acid replication and repair. The courses offered by the Unit are designed to equip students with a detailed understanding of modern concepts in genetics, virology and molecular biology and the ways in which these are brought to bear on the cancer problem. A good background in genetics and biochemistry is required of students. Graduate Record Examination scores in both the aptitude test (verbal and quantita- tive) and the advanced test in biology or chemistry are also required. Course work in the first year of graduate study is decided upon by students, in consultation with advisors provided by the Unit. Some courses in other Units of the Sloan-Kettering Division may be recommended, depending on the individual student's background. All students are also required to take three seminar courses and to carry out minor research projects in laboratories other than that of their major sponsor. A rotation program exists to aid students in choosing their major thesis topic and sponsor. Special Interests of the Faculty L. H. Augenlicht: Transcriptional control; eukaryotes I. Balazs: RNA processing F. C. Bancroft: Gene expression in endocrine cells P. Besmer: Gene transformation L. F. Cavalieri: Mutagens and carcinogenesis S. Y. Chen-Kiang: Virus transcription R. K. Cross: Viral genetics N. G. Famulari: Leukemogenesis E. Flessner: Oncogenic RNA viruses S. L. Gupta: Interferon action W. D. Hardy Jr.: Feline lymphosarcoma W. S. Hayward: Oncogene regulation and expression R. M. Krug: Molecular biology of viral gene expression P. W. Melera: Gene expression and amplification M. J. Modak: Structure-function relationship in DNA biosynthesis P. V. O'Donnell: Characterization of leukemia viruses A. I. Oliff: Genetic susceptibility to neoplasms A. Pinter: Structure and function of virus-coded proteins 0. Prakash: Reovirus replication J. V. Ravetch: Molecular biology of gene expression B. H. Rosenberg: DNA synthesis N. H. Sarkar: RNA oncogenic viruses G. C. Sen: Gene expression in eukaryotic cells E. Stavnezer: Eukaryotic genomes; RNA synthesis J. M. Stavnezer: Gene structure, rearrangement and transcription G. Stohrer: Carcinogenesis and cell differentiation Courses 1. Molecular Biology The course presents the fun- damentals of eukaryote gene structure, expression and regulation. Topics discussed include: DNA se- quence organization, chromatin structure, viral and cellular RNA transcription, translation and its regula- tion, control of gene expression in model systems and molecular aspects of carcinogenesis. 1, 2nd & 3rd trimester. G. C. Sen, J. Stavnezer and staff 2. Molecular Virology A formal course in which ma- jor emphasis is placed on the basic mechanisms in the biology of all animal viruses, including RNA and DNA tumor viruses. The topics considered include virus structure and composition, assay of viruses and viral-specific products, transcription and replication of viral nucleic acids, translation of virus-specific pro- teins, assembly of viral particles, structural and functional alterations in viral-infected cells including transformation, pathogenesis of viral diseases, and viral genetics. Alternate years. R. M. Krug and E. Stavnezer 3. Molecular Biology of Neoplastic Transforma- tion This course will focus on current efforts to understand the neoplastic cell phenotype from a mo- lecular point of view. The effects of RNA and DNA tumor viruses on host cells will be discussed, in par- ticular the transformation and or differentiation Mocks of defined cell lineages by certain agents. The nature and enzymatic specificities of viral gene products re- sponsible for transformation will be compared with related products of normal cellular genes. The poten- tial interaction of such products with regulatory systems controlling cell shape, adhesiveness, motility, and mitosis will be described, as well as the possible 30 Interdivisional Course involvement of the same systems in nonviral neo- plasias. At least part of the course will consist of student presentations on relevant subjects. Alternate years. Third trimester. E. Fleissner, P. Besmer, W. S. Hayward and staff 4. Advanced Molecular Genetics A seminar course for advanced students covering those areas of gene structure and expression in which rapid progress is being made. Second trimester. Staff. Medical Scientist Training Program This M.D.-Ph.D. program is sponsored collectively by the Sloan-Kettering Division, The Rockefeller Univer- sity, and Cornell University Medical College. Accepted students are required to demonstrate a strong under- graduate science preparation, and an early commitment to a career path combining both clinical and laboratory research. The program requirements include the research-based Sloan-Kettering Division Ph.D. curriculum, the Cornell University Medical College curriculum, and a number of tri-institutional special learning opportunities de- signed specifically for the Medical Scientist candidates. Applicants to this program simultaneously satisfy the separate requirements for admission to Cornell University Medical College and to the Sloan- Kettering Division, Graduate School of Medical Sci- ences. The following documentation should be submitted before November 30: 1 . Completed application forms 2. A personal letter summarizing background, inter- ests, and aims, and giving specific reasons for wishing to undertake this combined program. 3. Two letters of recommendation from persons well acquainted with the applicant who can attest to the applicant's suitability for a career in medicine. The recommendation of a premedical advisory commit- tee may be substituted for one of these letters. 4. One or more letters of recommendation from faculty members who can evaluate the applicant's potential for research. 5. Official transcripts of all undergraduate and gradu- ate studies, including summer school. 6. Results of Medical College Admissions Test and, if taken, Graduate Record Examination. Interdivisional Course Graduate Biochemistry Offered jointly by the fac- ulties of the Medical College and Sloan-Kettering Divisions. This course is designed to provide the stu- dent with a knowledge of the fundamentals of biochemistry and an appreciation of the molecular basis of biological phenomena. Graduate students in the Field of Biochemistry are required to pass this course (or its equivalent). Fall and winter trimesters. R H Haschemeyer, K. O Lloyd, and staff. Special Programs Ph.D.-M.D. Program Students enrolled in the Graduate School of Medical Sciences may be eligible for admission into the Ph D- M.D. Program, jointly sponsored by the Medical Col- lege and the Graduate School of Medical Sciences. This program is designed for those few graduate stu- dents whose teaching and research goals require the acquisition of the M.D. degree in addition to the Ph.D. degree. The program is not designed as an alternate path for students who have the M.D. degree as their primary goal, but who have not been accepted by a medical school. Those who know, at the time of ap- plication to Cornell, that they want to pursue a course of study leading to both degrees should apply to one of the M.D.-Ph.D programs of the Medical College described below. Only students enrolled in the Gradu- ate School of Medical Sciences, or accepted for enrollment, may apply for admission to the Ph.D.-M.D. Program at Cornell University Medical College. Requirements for Admission Applications to this program are ordinarily made after the completion of the first year of study in the Gradu- ate School of Medical Sciences, although more advanced students may be considered. The deadline for application is February 1. To apply, the student must submit to the Ph.D.-M.D. Committee of the Graduate School of Medical Sciences: 1. A completed application for admission with ad- vanced standing to Cornell University Medical College (obtainable from the Medical College Admissions Office). 2. A plan of graduate study incorporating ah required course work of the first two years of the Medical College curriculum and endorsed by the student's Special Committee. 3. Evidence of successful completion of at least two major medical school basic science courses (anatomi- cal sciences, biochemistry, microbiology, pathology, pharmacology, physiology). 4. Two letters of evaluation from faculty of the Gradu- ate School of Medical Sciences. The Ph.D.-M.D. Committee of the Graduate School of Medical Sciences will review the student's credentials and will select from among the applicants those stu- dents to be considered by the Committee on Admissions of Cornell University Medical College. Only applicants who are found to be acceptable for admission to Cornell University Medical College by its Committee on Admissions, after review of the applica- tion and a personal interview, will be accepted into the Ph.D-M.D Program. Final decisions will be made be- fore June 1. Degree Requirements Students accepted in this program must fulfill the fol- lowing requirements before admission to the third year clinical curriculum of the Medical College: 1. Complete all required graduate courses and the remainder of the first two years of the medical curricu- lum. The students must satisfy the academic requirements of the medical curriculum as these are determined by each of the departments of the first two years. 2. Pass the Admission to Candidacy Examination re- quired by the Graduate School of Medical Sciences. 3. Complete the dissertation research; present and successfully defend an original thesis at the final ex- amination for the Ph.D. degree. Special Programs 31 After satisfactory fulfillment of the required clinical ro- tations of the Cornell third-year medical curriculum, these students may receive credit for their graduate studies to satisfy the elective requirements of the fourth-year curriculum and will then be recommended for award of the M.D. degree by Cornell University While registered as a graduate student in the Ph.D.- M.D. program the student is subject to the tuition schedule of the Graduate School of Medical Sciences. Upon completion of the requirements for the Ph.D. degree, the student is registered in the Medical Col- lege and is subject to the tuition schedule of the Cornell University Medical College. M.D.-Ph.D. Program Programs of study leading to the Ph.D. degree are available to (1) students entering Cornell University Medical College, (2) medical students already ma- triculated at the Medical College, and (3) resident physicians in hospitals affiliated with the Medical College. Entering Medical Students The applicant to this program for entering medical students must apply to both the Cornell University Medical College and the Graduate School of Medical Sciences and be accepted through admissions pro- cedures of both schools. The purpose of this program is to expose the student to both medical and graduate disciplines from the outset. The student spends the first two years as a medical student studying the basic medical sciences and attending regular graduate seminars. The sum- mer months are sp^nt in the laboratory learning experimental techniques and doing research. The third, fourth, and fifth years of the student's program are spent as a full-time graduate student and are devoted exclusively to laboratory research and writing the thesis. The sixth year of the program is spent as a medical student in clinical study. This six-year pro- gram represents the minimum time required to satisfy residence requirements of both the M.D. and Ph.D. degrees at Cornell University. Ordinarily an entering medical student accepted into the M.D.-Ph.D. program will initially register in both the Cornell University Medical College and the Gradu- ate School of Medical Sciences. For the first and second years of the program, the student ordinarily will maintain registration as a full-time medical stu- dent. The student may accumulate residence credit in the Graduate School of Medical Sciences for full-time graduate study during the summer. During the third and fourth years of the M.D.-Ph.D. program, a student ordinarily will be registered as a full-time graduate student. In general, a student will be registered in both the Cornell University Medical Col- lege and the Graduate School of Medical Sciences during the last year of study for the Ph.D., which in most cases will be the fifth year of the program Dur- ing the final year of the program, usually the sixth year, a student will be registered only in the Cornell University Medical College. A student in the M.D.-Ph.D. program is liable for tui- tion to the school in which registered. During the year in which the student is registered in both the Cornell University Medical College and the Graduate School of Medical Sciences, the student will be liable for half the tuition to each school. Medical Scientist Training Program: This M.D - Ph.D. program is offered by the Sloan-Kettenng Divi- sion of the Graduate School of Medical Sciences with Cornell University Medical College and is described on p. 30. Matriculated Medical Students A medical student enrolled in the Cornell University Medical College may interrupt medical studies at any time to pursue full-time graduate study leading to the Ph.D. degree. The student must fulfill all regular re- quirements of the Graduate School of Medical Sciences. A maximum of two residence credits for basic sciences course work taken in the medical cur- riculum can be granted toward the Ph.D degree after the student passes an evaluation examination. A medical student who elects to begin graduate wor« leading to the Ph.D. degree in the senior year of medical school may register in both the Cornell Uni- versity Medical College and the Graduate School of Medical Sciences. The student begins his or her grad- uate didactic work during that year, and, ordinarily, the M.D. degree is granted at the end of that year. Re- search in the area of the Ph.D. thesis topic is begun during the fifth year. A two-year period of full-time research is a realistic minimum estimate for the time required to execute the experimental and theoretical work necessary to fulfill the requirements for the Ph.D. degree. Resident Physicians The resident physician may apply for admission to the Graduate School of Medical Sciences as a full-time graduate student working toward the Ph.D. Part-time graduate study is not permitted. A maximum of two residence credits for medical school course work in the basic sciences can be granted toward the resi- dence requirements of the Ph.D. degree after the student passes an evaluation examination. Prospective applicants to these programs should com- municate with the Dean of the Graduate School of Medical Sciences. 32 Cornell University Graduate School of Medical Sciences Register University Administration Frank H. T. Rhodes, President of the University W. Keith Kennedy, University Provost Thomas H. Meikle, Jr., Provost for Medical Affairs William G. Herbster, Senior Vice President Robert Barker, Vice President for Research and Ad- vanced Studies William D. Gurowitz, Vice President for Campus Affairs Robert T. Horn, Vice President, Treasurer, and Chief Investment Officer Robert M. Matyas, Vice President for Facilities and Business Operations Richard M. Ramin, Vice President for Public Affairs Alison P. Casarett, Vice Provost Larry \. Palmer, Vice Provost James W. Spencer, Vice Provost Walter J. Relihan, Jr., Secretary of the Corporation and University Counsel Neal R. Stamp, Senior Counsel to the University James A. Sanderson, Chief Investment Officer Graduate School of Medical Sciences Administration Frank H. T. Rhodes, President of the University Alison P. Casarett, Dean of the Graduate School Dieter H. Sussdorf, Acting Dean of the Graduate School of Medical Sciences and Acting Associate Dean of the Graduate School Richard A. Rifkind, Director, Sloan-Kettering Division Dorris J. Hutchison, Associate Director, Sloan-Ketter- ing Division; Associate Dean of the Graduate School of Medical Sciences, Assistant Dean of the Graduate School Faculty Abbott, Joan, Assistant Professor of Immunobiology. B.A. 1954, Connecticut College; M A. 1957, Wash- ington University; Ph.D. 1965, University of Pennsylvania Alcock, Nancy W., Assistant Professor of Develop- mental Therapy & Clinical Investigation. B.S. 1949, University of Tasmania (Australia); Ph D. 1960, Uni- versity of London (England) Allen, Fred H. Jr., Clinical Associate Professor of Pedi- atrics, A.B., 1934, Amherst College; M.D. 1938, Harvard University Allfrey, Vincent G., Adjunct Professor of Genetics, B.S. 1943, City College of New York; M.S. 1948, Ph.D. 1949, Columbia University Alonso, Daniel R., Associate Professor of Pathology. M.D. 1962, University of Cuyo (Argentina) Andersen, Olaf S., Professor of Physiology and Bio- physics. Candidatus Medicinae 1971, University of Copenhagen (Denmark) Anderson, Lowell L., Assistant Professor of Develop- mental Therapy & Clinical Investigation. B.S. 1953, Whitworth College; Ph.D. 1958, University of Rochester Artzt, Karen, Associate Professor of Cell Biology & Genetics. A.B. 1964, Ph.D. 1972, Cornell University Augenlicht, Leonard H., Assistant Professor Molecular Biology & Virology. B.A. 1967, State University of New York at Binghamton; Ph.D. 1971, Syracuse University Bachvarova, Rosemary F, Associate Professor of Cell Biology and Anatomy. B.A. 1961, Radcliffe College; Ph.D., 1966, Rockefeller University Bader, David M., Assistant Professor of Cell Biology and Anatomy. B.A. 1974, Augustana College; Ph.D. 1978, University of North Dakota Baker, Harriet D., Assistant Professor of Neurology. B.A. 1963, Wells College; M.S. 1967, University of Illinois; Ph.D. 1976, University of Iowa Balazs, Ivan, Assistant Professor of Molecular Biology & Virology. Ph.D. 1972, Albert Einstein College of Medicine Balis, M. Earl, Professor of Cell Biology & Genetics. B.A. 1943, Temple University; Ph.D. 1949, Univer- sity of Pennsylvania Bancroft, F. Carter, Associate Professor of Molecular Biology & Virology. B.S. 1959, Antioch College; M.A. 1961, Johns Hopkins University; Ph.D. 1966, University of California at Berkeley Becker, Carl G., Professor of Pathology. B.S. 1957, Yale University; M.D. 1971, Cornell University Bedford, J. Michael., Professor of Cell Biology and Anatomy. B.A. 1955, M.A. Vet. M.B. 1958, Cambridge University (England); Ph.D. 1965, Uni- versity of London (England) Bennett, Dorothea, Professor of Cell Biology & Genet- ics. A.B. 1951, Barnard College; Ph.D. 1956, Columbia University Besmer, Peter, Assistant Professor of Molecular Biol- ogy & Virology. M.S. 1964; Ph D 1969, Eidgenbssische Technische Hochschule (Switzerland) Bianco, Celso, Adjunct Professor of Cell Biology. M.D. 1966, Escola Paulista de Medicina (Sao Paulo, Brazil) Register 33 Biedler, June L, Professor of Cell Biology & Genetics. A.B. 1947, Vassar College; Ph.D. 1959, Cornell University Bigler, Rodney E., Assistant Professor of Developmen- tal Therapy & Clinical Investigation. B.S. 1966, Portland State University; Ph.D. 1971, University of Texas Black, Ira B., Professor of Neurology. A.B. 1961, Co- lumbia College; M.D. 1965, Harvard University Blass, John P., Professor of Neurology and Medicine, A. B. 1958, Harvard University, Ph.D. 1960, Univer- sity of London (England), M.D. 1965, Columbia University Bockman, Richard S., Assistant Professor of Cell Biol- ogy & Genetics. B.A. 1962, Johns Hopkins University; M.D. 1967, Yale University; Ph.D. 1971, Rockefeller University Borenfreund, Ellen, Associate Professor of Cell Biol- ogy & Genetics. B.S. 1946, Hunter College; Ph.D. 1957, New York University Boskey, Adele L, Assistant Professor of Biochemistry. B. A. 1964, Barnard College; Ph.D. 1970, Brown University Boyse, Edward A., Professor of Immunobiology. M.B.B.S. 1952, M.D. 1957, University of London (England) Breslow, Esther M., Professor of Biochemistry. B.S. 1953, Cornell University; M S. 1955, Ph.D. 1959, New York University Briscoe, William A., Professor of Medicine. B.A. 1939, M.A. 1941, B.M.B.Ch. 1942, D.M. 1951, Oxford Uni- versity (England) Brooks, Dana C, Professor of Cell Biology and Anat- omy. B.E.E. 1949, M.D. 1957, Cornell University Bullough, Peter, Associate Professor of Pathology. M.D. 1956, Liverpool University (England) Cavalieri, Liebe R, Professor of Molecular Biology & Virology. B.S. 1943, Ph.D. 1945, University of Pennsylvania Chaganti, Raju S., Assistant Professor of Cell Biology & Genetics. B.S. 1954, M.S. 1955, Andhra Univer- sity (India); Ph.D. 1964, Harvard University Chan, Walter W. Y, Professor of Pharmacology. B.A. 1956, University of Wisconsin; Ph.D. 1961, Colum- bia University Chen-Kiang, Selina Y. Assistant Professor of Molecu- lar Biology & Virology. B.S. 1965, National Taiwan University, Ph.D. 1977, Columbia University Choi, Yong Sung, Professor of Immunobiology. M.D. 1961, Seoul National University (Korea); M.S., Ph.D. 1965, University of Minnesota Chou, Ting-Chao, Associate Professor of Develop- mental Therapy & Clinical Investigation. B.S. 1961, Kaohsiung Medical College (Taiwan); M.S. 1965, National Taiwan University; Ph.D. 1970, Yale University Cooper, Arthur J. L . Associate Professor of Bio- chemistry in Neurology. B.Sc. 1967, M.Sc. 1969, University of London (England); Ph.D. 1974, Cornell University Cornell, James S.. Associate Professor of Biochemis- try. B.S. 1969, Michigan State University; Ph.D. 1973, University of California at Los Angeles Cunningham-Rundles, Charlotte, Assistant Professor of Immunobiology. B.S 1965, Duke University; M.D. 1969, Columbia College of Physicians and Sur- geons; Ph D 1974, New York University Danes, B. Shannon, Associate Professor of Medicine. B.A. 1948, Mount Holyoke College; M.A. 1949, Uni- versity of Texas; Ph.D. 1952, State University of Iowa; M.D. 1962, Columbia University Darzynkiewicz, Zbigniew, Associate Professor of Cell Biology & Genetics. M.D. 1960, Academy of Medi- cine, Warsaw (Poland); Ph.D. 1965, Academy of Medicine and Polish Academy of Sciences (Poland) Deschner, Eleanor E., Assistant Professor of Cell Biol- ogy & Genetics. B.A. 1949, Notre Dame of Staten Island; M.S. 1951, Ph.D. 1954, Fordham University De Sousa, Maria A. B., Associate Professor of Immu- nobiology. M.D. 1963, Lisbon Medical Faculty (Portugal); Ph.D. 1971, University of Glasgow (Scot- land); M.R.C. 1973, Royal College of Pathologists (England) Dickerman, Robert W., Associate Professor of Micro- biology. B.S. 1951, Cornell University; M.A. 1953, University of Arizona; Ph.D. 1961, University of Minnesota Donner, David B., Assistant Professor of Cell Biology & Genetics. B.A. 1966, Queens College; Ph.D. 1972, Rensselaer Polytechnic Institute Duffy, Thomas E., Associate Professor of Biochemis- try in Neurology; Assistant Professor of Biochemistry (Neurology). B.S. 1962, Loyola Univer- sity; Ph.D. 1967, University of Maryland Dupont, Bo, Professor of Immunobiology. M.D. 1966, University of Arhus (Denmark) Eisinger, Magdalena G., Assistant Professor of Cell Biology & Genetics. D.V.M. 1962, Agricultural Ur,. versity Kosice (Czechoslovakia) Ellis, John T, Professor of Pathology. B.A. 1942, Uni- versity of Texas; M.D. 1945, Northwestern University Evans, Robert L, Assistant Professor of Immunobiol- ogy. M.D. 1972, University of Washington Fairclough, Gordon F, Associate Professor of Bio- chemistry. B.A. 1960, Ph.D. 1966, Yale University Famulari. Nancy G., Assistant Professor of Molecular Biology & Virology. B.A. 1969, Colby College; Ph.D. 1974, Cornell University Fell, Colin, Associate Professor of Physiology and Bi- ophysics. B.A. 1951, Antioch College; M.S. 1953, Ph.D. 1957, Wayne State University Felsen, Diane F, Assistant Professor of Pharmacology in Surgery. B.A. 1974, Queens College; Ph.D. 1979, Mt. Sinai School of Medicine Fischman, Donald A., Professor of Cell Biology and Anatomy (Chairman). Harvey Klein Professor of Bio- medical Sciences. A.B. 1957, Kenyon College; M.D. 1961, Cornell University Fleisher, Martin, Assistant Professor of Developmental Therapy & Clinical Investigation. B.A. 1958, Harpur College; Ph.D. 1966, New York University Fleissner, Erwin, Professor of Molecular Biology & vi- rology. B.A. 1957, Yale University; Ph.D. 1963, Columbia University Fogh, Jorgen E., Associate Professor of Cell Biology & Genetics. M.D. 1949, University of Copenhagen (Denmark) Fox, Jack J., Professor of Developmental Therapy & Clinical Investigation. A.B. 1939, Ph D 1950, Uni- versity of Colorado Fried, Jerrold, Associate Professor of Developmental Therapy & Clinical Investigation. B.S. 1958. Califor- nia Institute of Technology: Ph.D. 1964. Stanford University 34 Register Friedman, Eileen A., Assistant Professor of Cell Biol- ogy & Genetics. A.B. 1967, New York University; Ph.D. 1972, Johns Hopkins University Frindt, Gustavo, Assistant Professor of Physiology and Biophysics. M.D. 1963, Catholic University of Chile Gardner, Daniel, Associate Professor of Physiology and Biophysics. A.B. 1966, Columbia College; Ph.D. 1971, New York University Gass, Jerald D., Associate Professor of Biochemistry. B.S. 1957, University of Oklahoma; A.M. 1962, Har- vard University; Ph.D. 1969, Cornell University Gazzaniga, Michael S., Professor of Neuropsychology in Neurology. A.B. 1961, Dartmouth College; Ph.D. 1964, California Institute of Technology Gelbard, Allan S., Associate Professor of Develop- mental Therapy & Clinical Investigation. B.S. 1955, Brooklyn College, M.S. 1956, University of Mas- sachusetts; Ph.D. 1959, University of Wisconsin Geller, Nancy L, Assistant Professor of Developmen- tal Therapy & Clinical Investigation. B.S. 1965, City University of New York; M.A. 1967, Case Institute of Technology; Ph.D. 1972, Case Western Reserve University German, James L. Ill, Clinical Professor of Pediatrics; Clinical Professor of Medicine. B.S. 1945, Louisiana Polytechnic Institute; M.D. 1949, Southwestern Medical College Gibbs, James G. Jr., Associate Professor of Psychia- try. B.S. 1960, Trinity College; M.D. 1964, Medical College of South Carolina Gibson, Gary E., Associate Professor of Neurology. B.S. 1968, University of Wyoming; Ph.D. 1973, Cor- nell University Gilder, Helena, Associate Professor of Biochemistry in Surgery; Assistant Professor of Biochemistry. A.B. 1935, Vassar College; M D. 1940, Cornell University Girgis, Fakhry, Associate Professor of Cell Biology and Anatomy. M.B.B.Ch. 1949, Cairo University (Egypt); Ph.D. 1957, Queen's University (Northern Ireland) Goldstein, Jack, Associate Professor of Biochemistry. B.A. 1952, Brooklyn College; M.N.S. 1957, Ph.D. 1959, Cornell University Graf, Lloyd H. Jr., Assistant Professor of Genetics in Obstetrics and Gynecology. B.S. 1967 and Ph.D. 1972, Duke University Grafstein, Bernice, Professor of Physiology and Bio- physics. B.A. 1951, University of Toronto (Canada); Ph.D. 1954, McGill University (Canada) Greif, Roger L., Emeritus Professor of Physiology and Biophysics. B.S. 1937, Haverford College; M.D. 1941, Johns Hopkins University Griffith, Owen W., Associate Professor of Biochemis- try. B.A. 1968, University of California at Berkeley; Ph.D. 1976, Rockefeller University Groshen, Susan, Assistant Professor of Developmen- tal Therapy & Clinical Investigation. A.B. 1973, Cornell University; M.S. 1976, Ph.D. 1978, Rutgers University Gupta, Sohan Lai, Assistant Professor of Molecular Biology & Virology. M.S. 1960, Ahgarh Muslim Uni- versity, Ahgarh (India); Ph.D. 1967, All India Institute of Medical Sciences, New Delhi (India) Hagamen, Wilbur D., Professor of Cell Biology and Anatomy. B.S. 1945, Baldwin-Wallace College; M.D. 1951, Cornell University Hajjar, David, Assistant Professor of Pathology. B.A. 1974, American International College; M.S. 1977, Ph D 1978, University of New Hampshire Halmi, Katherine A., Associate Professor of Psychia- try. B.A. 1961, University of Iowa; M.D. 1965, University of Iowa Hamburg, Martin D., Adjunct Associate Professor of Cell Biology and Anatomy. B.A. 1965, New York University; Ph.D. 1969, University of Michigan Hammerling, Ulrich, Associate Professor of Immu- nobiology. Diplom 1961 Universitat Freiburg (Germany); Ph.D. 1965, Max Planck Institut fur Im- munobiologie (Germany) Hardy, William D. Jr., Assistant Professor of Molecular Biology & Virology. A.A. 1969, B.S. 1962, George Washington University; V.M.D. 1966, University of Pennsylvania Haschemeyer, Rudy H., Professor of Biochemistry. B.A. 1952, Carthage College; Ph.D. 1957, Univer- sity of Illinois Hayward, William S., Professor of Molecular Biology & Virology. B.A. 1964, University of California, River- side; Ph.D. 1969, University of California, San Diego Heinz, Erich, Professor of Physiology and Biophysics. M.D. 1939, University of Munster and Kiel (Germany) Higgins, Paul J., Assistant Professor of Cell Biology & Genetics. B.S. 1969, lona College; M.S. 1973, Long Island University; Ph.D. 1976, New York University Hinkle, Lawrence E. Jr., Professor of Medicine; Pro- fessor of Medicine in Psychiatry. Attending Physician, New York Hospital. B.A. 1938, University of North Carolina; M.D. 1942, Harvard University Hirshaut, Yashar, Assistant Professor of Developmen- tal Therapy & Clinical Investigation. B.A. 1959, Yeshiva University; M.D. 1963, Albert Einstein Col- lege of Medicine Hoffman, Hans-Peter, Adjunct Assistant Professor of Genetics. B.A. 1968, Ph.D. 1968, Rutgers University Hoffmann, Michael K., Associate Professor of Immu- nobiology. M.D. 1966, Universitat Tubingen (Germany) Horecker, Bernard L., Adjunct Professor of Biochemis- try. B.S. 1936, Ph.D. 1939, University of Chicago Hosein, Barbara H., Adjunct Assistant Professor. Pro- fessor of Cell Biology and Anatomy. B.A. 1969, University of Kansas; M.S. 1971, Ph.D. 1973, Uni- versity of Michigan Houde, Raymond W., Associate Professor of Phar- macology. A.B. 1940, M.D. 1943, New York University Hutchison, Dorris J., Professor of Cell Biology & Ge- netics. B.S. 1940, Western Kentucky State College; M.S. 1943, University of Kentucky; Ph.D. 1949, Rutgers University Incefy, Genevieve S., Assistant Professor of Immu- nobiology. B.Sc. 1959, M.Sc. 1960, Ph.D. 1964, Ohio State University Inturrisi, Charles E., Professor of Pharmacology. B.S. 1962, University of Connecticut; M.S. 1965; Ph.D. 1967, Tulane University Javitt, Norman B., Professor of Medicine. A.B. 1947, Syracuse University; Ph.D. 1951, University of North Carolina; M.D. 1954, Duke University Joh, Tong Hyub, Professor of Neurobiology in Neurol- ogy. B.S. 1953, Seoul National University (Korea); Ph.D. 1971, New York University Register 35 Johnson, Edward M., Adjunct Assistant Professor of Genetics. B.A. 1967, Pomona College; Ph.D. 1971, Yale University Jones, Brian R., Assistant Professor of Pharmacology. B.Sc. 1970, University of London (England); M.B.B.S. 1973, St. Marys Hospital School of the University of London (England) Jones, Thomas Clifford, Professor of Medicine. B.A. 1958, Allegheny College; M.D. 1962, Case Western Reserve University Kaiko, Robert R, Adjunct Assistant Professor of Phar- macology. B.S. 1970, University of Connecticut; Ph.D. 1974, Cornell University Kaplan, Barry B., Associate Professor of Cell Biology and Anatomy. B.A. 1968, M A. 1969, Hofstra Univer- sity; Ph.D. 1974, Cornell University Keithly, Jan S., Assistant Professor of Microbiology, Assistant Professor of Microbiology in Medicine. B.S. 1963, Central Missouri State University, Ph.D. 1968, Iowa State University Kellner, Aaron, Clinical Professor of Pathology. B. A. 1934, Yeshiva College; M.S. 1936, Columbia Uni- versity; M.D. 1939, University of Chicago Kim, Jae Ho, Associate Professor of Developmental Therapy & Clinical Investigation. M.D. 1959, Kyungpook National School of Medicine (Korea); Ph.D. 1963, State University of Iowa Kim, Yoon B., Professor of Immunobiology M.D. 1958, School of Medicine, Seoul National University (Korea); Ph.D. 1965, University of Minnesota Koo, Gloria C, Assistant Professor of Immunobiology. B.A. 1965, Goshen College; Ph.D. 1970, Temple University Kopelovich, Levy, Associate Professor of Cell Biology & Genetics. B.S 1958, Hebrew University (Israel); Ph.D. 1962, University of California Kourides, lone A., Associate Professor of Cell Biology & Genetics. B.A. 1963, Wellesley College; M.D. 1967, Harvard University Krug, Robert M., Professor of Molecular Biology & Virology. B.A. 1961, Harvard University; Ph.D. 1966, Rockefeller University Kucherlapati, Raju S., Adjunct Assistant Professor. B.S. 1960, PR. College (India); M.S. 1962, Andhra University (India); Ph.D. 1972, University of Illinois Lai, Chun-Yen, Adjunct Professor of Biochemistry. B.S. 1953, M.S. 1957, National Taiwan University; Ph.D. 1961, University of Illinois Laughlin, John S., Professor of Developmental Therapy & Clinical Investigation. A.B. 1940, Willamette University, Ph.D. 1947, University of Illinois Lee, Chin Ok, Associate Professor of Physiology and Biophysics. M.S. 1967, Seoul National University (Korea); Ph.D. 1973, Indiana School of Medicine Levi, Roberto, Professor of Pharmacology. M.D. 1960, University of Florence (Italy) Levy, David E., Associate Professor of Neurology. A.B. 1963, M.D. 1968, Harvard University Lieberman, Kenneth W., Assistant Professor of Bio- chemistry in Psychiatry. B.A. 1960, Brooklyn College; M.S. 1963, Texas Technological College; Ph.D. 1966, University of Kentucky Lipkin. Martin, Professor of Medicine. A.B. 1946, M.D. 1950, New York University Litman, Gary W., Associate Professor of Immunobiol- ogy. B.A. 1967, Ph.D. 1972, University of Minnesota Lloyd, Kenneth O, Associate Professor of Immuno- biology. Ph.D. 1960, University College of North Wales (England) Lopez, Carlos, Associate Professor of Immunobiology B.A. 1965, M.S. 1966, Ph.D. 1970, University of Minnesota Maack, Thomas, Professor of Physiology and Bio- physics. M.D. 1962, University of Sao Paulo (Brazil) MacLeod, John, Emeritus Professor of Cell Biology and Anatomy. A.B. 1934, M.Sc. 1937, New York University; Ph.D. 1941, Cornell University Marks, Paul A., Professor of Cell Biology & Genetics. A. B. 1945, Columbia University; M.D. 1949, College of Physicians & Surgeons, Columbia University Mehta, Bipin M., Assistant Professor of Developmental Therapy & Clinical Investigation. B.Sc. 1955, M.Sc 1957, Ph.D. 1963, Bombay University (India) Meister, Alton, Israel Rogosin Professor of Biochemis- try. B.S. 1942, Harvard University; M.D. 1945, Cornell University Melamed, Myron R., Professor of Cell Biology & Ge- netics. B.S. 1947, Western Reserve University, M.D. 1950, University of Cincinnati Melera, Peter W., Assistant Professor of Molecular Biology & Virology. A.A.S. 1963, State University of New York at Cobleskill; B.S. A. 1965, Ph.D. 1969, University of Georgia Mellors, Robert C, Professor of Pathology. A.B. 1937, M.A. 1938, Ph.D., 1940, Western Reserve Univer- sity; M.D. 1944, Johns Hopkins University Meshnik, Steven R., Assistant Professor of Medicir.o. B. A. 1972, Columbia University; Ph.D. 1978, Rockefeller University Mike, Valerie, Professor of Developmental Therapy & Clinical Investigation. B.A. 1956, Manhattanville College; M.S. 1959, Ph.D. 1967, New York University Minick, C. Richard, Professor of Pathology. B.S. 1957, University of Wyoming; M.D. 1960, Cornell University Modak, Mukund J., Associate Professor of Molecular Biology & Virology. B.Sc. 1963, University of Poona (India); M.Sc. 1965, University of Bombay (India); Ph.D. 1969, Haffkine Institute, University of Bombay (India) Mohan, Radhe, Visiting Assistant Professor of Bio- physics. B.S. 1959, M.S. 1963, Punjabi University (India); Ph.D. 1969, Duke University Moon, Hong Mo, Adjunct Professor of Neurobiology B.S. 1961, Sung Kyun Kwan University (Korea); Ph.D. 1967, University of North Carolina Moore, Anne C, Assistant Professor of Cell Biology & Genetics. B.A. 1970, Carleton College; Ph.D. 1976, University of California, Berkeley Moore, Malcolm A. S., Professor of Cell Biology & Genetics. M. B. 1963, B.A. 1964, D.Phil. 1967, M.A. 1970, Oxford University (England) Muller-Eberhard, Ursula, Professor of Pediatrics; Pro- fessor of Pharmacology; M.D 1953, University of Gbttingen (Germany) Murphy, George E., Professor of Pathology. A.B. 1939. University of Kansas; M.D. 1943, University of Pennsylvania Nachman, Ralph L., Professor of Medicine. A.B. 1953. M.D. 1956, Vanderbilt University 36 Register Nisselbaum, Jerome S., Associate Professor of De- velopmental Therapy & Clinical Investigation. B.A. 1949, University of Connecticut; Ph.D. 1953, Tufts University Novogrodsky, Abraham, Associate Professor of Bio- chemistry. M.D. 1960, Hebrew University Medical School, Jerusalem; Ph.D. 1974, Weizmann Institute of Science, Rehovot (Israel) O'Donnell, Paul V., Assistant Professor of Molecular Biology & Virology. B.S. 1968, Rensselaer Poly- technic Institute; Ph.D. 1973, Cornell University Oettgen, Herbert R, Professor of Immunobiology. M.D. 1951, University of Cologne (Germany) Okamoto, Michiko, Professor of Pharmacology. B.S. 1954. Tokyo College of Pharmacy (Japan); M.S. 1957, Purdue University; Ph.D. 1964, Cornell University Old, Lloyd J., Professor of Immunobiology. B.A. 1955, M.D. 1958, University of California O'Leary, William M., Professor of Microbiology. B.S. 1952, M.S. 1953, Ph.D. 1957, University of Pittsburgh Oliff, Allen I., Assistant Professor of Molecular Biology & Virology. B.S. 1971, Brandeis University; M.D. 1974, Albert Einstein College of Medicine O'Reilly, Richard J., Assistant Professor of Immuno- biology. A.B. 1964, College of the Holy Cross; M.D. 1968, University of Rochester Otter, Brian J., Assistant Professor of Developmental Therapy & Clinical Investigation. B.Sc. 1962, Ph.D. 1965, University of Bristol (England) Pahwa, Rajendra N., Assistant Professor of Immuno- biology M.B.B.S. 1966, M.D. 1969, Indore Medical College (India) Palmer, Lawrence G., Assistant Professor of Physiol- ogy and Biophysics. B.A. 1970, Swarthmore College; Ph.D. 1976, University of Pennsylvania Pardee, Joel D., Assistant Professor of Cell Biology and Anatomy. B.S. 1973, Colorado State University; Ph.D. 1978, Stanford University Pasternak, Gavril W, Assistant Professor of Phar- macology. B.A. 1969, M.D. 1973, Ph.D. 1974, Johns Hopkins University Petito, Carol K., Associate Professor of Pathology. B.S. 1963, Jackson College; M.D. 1967, Columbia University Philips, Frederick S., Professor of Developmental Therapy & Clinical Investigation. B.A. 1936, Colum- bia University; Ph.D. 1940, University of Rochester Pickel, Virginia M., Professor of Neurology. B.S. 1965, M.S. 1967, University of Tennessee; Ph.D. 1970, Vanderbilt University Pickering, Thomas G., Associate Professor of Medi- cine B.A 1962, M A. 1968, Cambridge University (England); Ph.D. 1970, Oxford University (England) Pinter, Abraham, Assistant Professor of Molecular Bi- ology & Virology. B.Sc. 1969, Brooklyn College; Ph.D. 1973, Columbia University Platsoukas, Chris D., Assistant Professor of Immu- nobiology B.S. 1973, University of Patras (Greece); Ph D. 1978, Massachusetts Institute of Technology Plum, Fred, Anne Parrish Titzell Professor of Neurol- ogy B.A 1944, Dartmouth College; M.D. 1947, Cornell University Pollack, Marilyn S , Assistant Professor of Immuno- biology A.B 1961. M A 1963, University of California at Berkeley; Ph D 1968, Rutgers University Polley, Margaret J., Associate Research Professor in Medicine. B.S. 1953, University of Wales; Ph.D. 1964, University of London (England) Posner, Aaron S., Professor of Biochemistry. B.S. 1941, Rutgers University; M.S. 1949, Polytechnic Institute of Brooklyn; Ph.D. 1954, University of Liege (Belgium) Prince, Alfred M., Clinical Associate Professor of Pa- thology. A.B. 1949, Yale University; M.A. 1951, Columbia University; M.D. 1955, Western Reserve University Rabellino, Enrique M., Assistant Professor of Medi- cine. B.S. 1959, Institute J. M. Paz (Argentina); M.D. 1965, University of Cordoba (Argentina) Rachele, Julian R., Emeritus Professor of Biochemis- try. B.A. 1934, M.S. 1935, Ph.D. 1939, New York University Ralph, Peter M., Associate Professor of Cell Biology & Genetics. B.A. 1958, Yale University, M.A. 1960, University of California at Berkeley, Ph.D. 1968, Massachusetts Institute of Technology Ravetch, Jeffrey A., Assistant Professor of Molecular Biology & Virology. B.S. 1973, Yale University; Ph.D. 1978, Rockefeller University; M.D. 1979, Cor- nell Medical College Reidenberg, Marcus M., Professor of Pharmacology. B.S. 1954, Cornell University; M.D. 1958, Temple University Reis, Donald J., George C. Cotzias Distinguished Pro- fessor of Neurology. A.B. 1953, M.D. 1956, Cornell University Rifkind, Arleen B., Professor of Pharmacology; As- sistant Professor of Medicine, B.A. 1960, Bryn Mawr College; M.D. 1964, New York University Rifkind, Richard A., Professor of Cell Biology & Genet- ics. B.S. 1952, Yale University; M.D. 1955, Columbia University Riggio, Robert, Professor of Biochemistry. B.A. 1954, Dartmouth College; M.D. 1958, New York University Riker, Walter F. Jr., Professor of Pharmacology. B.S. 1939, Columbia University; M.D. 1943, Cornell University Risley, Michael, Assistant Professor of Cell Biology and Anatomy. B.S. 1970, Manhattan College; Ph.D. 1976, City University of New York Roberts, Joseph, Associate Professor of Developmen- tal Therapy & Clinical Investigation. B.Sc. 1959, University of Toronto (Canada); M.S. 1962, Univer- sity of Wisconsin; Ph.D. 1964, McGill University (Canada) Roberts, Richard B., Professor of Medicine. B.A 1955, Dartmouth College; M.D. 1959, Temple University Rodman, Toby C, Professor of Cell Biology and Anat- omy. B.S. 1937, Philadelphia College of Pharmacy and Science; M.S. 1961, Ph.D. 1963, New York University Rosenberg, Barbara, Associate Professor of Molecular Biology & Virology. B.S. 1950, Ph.D. 1962, Cornell University Rottenberg, David A., Associate Professor of Neurol- ogy. B A. 1963, University of Michigan; M.Sc. 1967, University of Cambridge (England); M.D. 1969, Har- vard University Rubin, Albert L., Professor of Biochemistry in Surgery, M.D. 1950, Cornell University Rubenstein, Pablo, Adjunct Associate Professor of Genetics Ph D 1964, Universidad de Chile Register 37 Sackin, Henry J., Assistant Professor of Physiology and Biophysics. B.S., B.A. 1970, M.S. 1971, Brown University; Ph D 1978, Yale University Safai, Bijan, Assistant Professor of Immunobiology. M.D. 1965, University of Teheran Medical School (Iran) Santos-Buch, Charles A., Professor of Pathology. A.B. 1953, Harvard University; M.D. 1957, Cornell University Sarkar, Nurul H., Associate Professor of Molecular Biology & Virology. B.S. 1957, M.S. 1960, Ph.D. 1966, University of Calcutta (India) Saxena, Brij B., Professor of Endocrinology in Obstetrics and Gynecology. Ph.D. 1954, University of Lucknow (India); D.Sc. 1957, University of Muenster (Germany); Ph.D. 1961, University of Wisconsin Scheid, Margrit P., Associate Professor in Immunobiol- ogy. M.D. 1970, Physiologisches Institut der Freien Universitat Berlin (Germany) Schneider, Allan S., Associate Professor of Cell Biology & Genetics. B.Ch.E. 1961, Rensselaer Poly- technic Institute; M.S. 1963, Pennsylvania State University, Ph.D. 1968, University of California at Berkeley Schoenfeld, William N., Adjunct Professor of Psychol- ogy in Psychiatry. B.S. 1937, City College of New York; A.M. 1939, Ph.D. 1942, Columbia University Schubert, Edward T., Assistant Professor of Bio- chemistry in Pediatrics. B.S. 1949, M.S. 1952, Ph.D. 1959, Fordham University Schwartz, Morton K., Professor of Developmental Therapy & Clinical Investigation. B.A. 1948, Lehigh University; Ph.D. 1952, Boston University Sechzer, Jeri A., Associate Professor of Psychology in Psychiatry. B.S. 1956, New York University; M.A. 1961, Ph.D. 1962, University of Pennsylvania Sen, Ganes C, Assistant Professor of Molecular Biol- ogy & Virology. B.S. 1965, M.S. 1967, Calcutta University (India); Ph.D. 1974, McMaster University (Canada) Senterfit, Laurence B., Associate Professor of Micro- biology. B.S. 1949, M.S. 1950, University of Florida; Sc.D. 1955, Johns Hopkins University Shapiro, Joan Rankin, Assistant Professor of Cell Biol- ogy in Neurology. B.S. 1960, Westminster College; M.S. 1968, New York University; M.A. 1970, Hofstra University; Ph.D. 1979, Cornell University Shen, Fung-Win, Assistant Professor of Immunobiol- ogy. B.S. 1968, Fu-Jen Catholic University (Taiwan); M.S. 1971, Ph.D. 1973, University of New Mexico Sherman, Merry R., Associate Professor of Cell Biol- ogy & Genetics. B.A. 1961, Wellesley College; M.A. 1963, Ph D 1966, University of California at Berkeley Silagi, Selma, Professor of Genetics in Obstetrics and Gynecology. A.B. 1936, Hunter College; Ph.D. 1961, Columbia University Silverstone, Allen E., Assistant Professor of Cell Biol- ogy & Genetics. B.A. 1964, Reed College; Ph.D. 1970, Massachusetts Institute of Technology Siniscalco, Marcello, Professor of Cell Biology & Ge- netics. M.D. 1948. University of Naples (Italy) Sirlin, Julio L, Professor of Cell Biology and Anatomy. D.Sc. 1953, University of Buenos Aires (Argentina) Sirotnak, Francis M., Professor of Developmental Therapy & Clinical Investigation. B.S. 1950, Univer- sity of Scranton: Ph.D. 1954, Univers^y of Maryland Siskind, Gregory W., Professor of Medicine. B.A. 1955, Cornell University; M.D. 1959, New York University Smith, Gerard P., Professor of Psychiatry (Behavioral Science). B.S. 1956, St. Joseph's College; M.D. 1960, University of Pennsylvania Softer, Richard L., Professor of Biochemistry and Med- icine. B.A. 1954, Amherst College; M.D. 1958, Harvard University Sonenberg, Martin, Professor of Cell Biology & Genet- ics. B.S. 1941, University of Pennsylvania; M.D. 1944, Ph.D. 1952, New York University Stavnezer, Edward, Assistant Professor of Molecular Biology & Virology. B.A. 1965, M.S. 1967, University of Connecticut, Ph.D. 1971, Johns Hopkins University Stavnezer, Janet, Assistant Professor of Molecular Bi- ology & Virology B.A. 1966, Swarthmore College; Ph.D. 1971, Johns Hopkins University Stenzel, Kurt H., Professor of Medicine; Professor of Biochemistry in Surgery. B.S. 1954, New York Uni- versity; M.D. 1958, Cornell University Sternberg, Stephen S., Professor of Developmental Therapy & Clinical Investigation. B.A. 1941, Colby College; M.D. 1944, New York University Sterner, Richard, Adjunct Assistant Professor of Ge- netics. B.A. 1968, University of California, Berkeley; M.S. 1969, Ph.D. 1970, University of Chicago Stbhrer, Gerhard, Associate Professor of Molecular Biology & Virology. Ph.D. 1965, Freie Universitat Berlin (Germany) Stokes, Peter E., Associate Professor of Medicine arv. Psychiatry. B.S. 1948, Trinity College; M.D. 1952, Cornell University Stutman, Osias, Professor of Immunobiology. B.A. 1950, Colegio Nacional Sarmiento (Argentina); M.D. 1957, Buenos Aires University Medical School (Argentina) Sullivan, Karen A., Assistant Professor of Immunobiol- ogy. B.S. 1966, North Adams State College; Ph.D. 1973, Duke University Sussdorf, Dieter H., Associate Professor of Microbiol- ogy. B.A. 1952, University of Missouri; Ph.D. 1956, University of Chicago Swan, Roy C, Joseph C. Hinsey Professor of Cell Biology and Anatomy. A.B. 1941, M.D. 1947, Cornell University Szeto, Hazel H., Associate Professor of Pharmacol- ogy. B.S. 1972, Indiana University; Ph.D., M.D. 1977, Cornell University Tate, Suresh S., Associate Professor of Biochemistry. B.Sc. 1958, M.Sc. 1960, University of Baroda (In- dia); Ph.D. 1963, University of London (England) Teitelman, Gladys N., Assistant Professor of Neuro- biology in Neurology. Licenciada in Biology 1962. University of Buenos Aires (Argentina); Ph.D. 1971, University of Pennsylvania Thaler, Howard T, Assistant Professor of Developmen- tal Therapy & Clinical Investigation. B.A. 1967, University of California at Los Angeles; Ph D 1974, State University of New York at Buffalo Trotta, Paul P., Assistant Professor of Biochemistry. A.B. 1964, Columbia University; Ph.D. 1968. State University of New York Downstate Medical Center Tung, Jwu-Sheng, Assistant Professor of Immunobiol- ogy B.A. 1959, National Taiwan University (Taiwan); M.S. 1966, Ph.D. 1971, University of California at Berkeley 38 Register Udenfriend, Sidney, Adjunct Professor of Biochemistry. B.S. 1939, City College of New York; M.S. 1942, Ph.D. 1948, New York University Watanabe, Kyoichi A., Professor of Developmental Therapy & Clinical Investigation. Ph.D. 1963, Hok- kaido University (Japan) Weinstein, Alan M., Assistant Professor of Physiology and Biophysics. A.B. 1971, Princeton University; M.D. 1975, Harvard University Weksler, Babette B., Professor of Medicine. B.A. 1958, Swarthmore College; M.D. 1963, Columbia University Weksler, Marc E., Irving Sherwood Wright Professor of Geriatrics; Professor of Medicine. B.A. 1958, Swarthmore College; M.D. 1962, Columbia University Wellner, Daniel, Associate Professor of Biochemistry. A.B. 1956, Harvard University; Ph.D. 1961, Tufts University Wiebe, Michael E., Assistant Professor of Microbiol- ogy. B.A. 1965, Sterling College; Ph.D. 1971, University of Kansas Winchester, Robert J., Adjunct Associate Professor of Genetics. B.S. 1958, Manhattan College; M.D. 1963, Cornell University Windhager, Erich E., Maxwell M. Upson, Professor of Physiology and Biophysics. M.D. 1954, University of Vienna (Austria) Woods, Kenneth R., Associate Professor of Bio- chemistry. B.A. 1948, Arizona State University; Ph.D. 1955, University of Minnesota Yip, Lily C, Assistant Professor of Cell Biology & Genetics. Ph.D. 1965, University of Cincinnati Zakim, David, Vincent Astor Distinguished Professor of Medicine; B.A. 1956, Cornell University; M.D. 1961, State University of New York Downstate Medi- cal Center Zedeck, Morris S., Associate Professor of Cell Biology & Genetics. B.S. 1961, Brooklyn College of Phar- macy; Ph.D. 1965, University of Michigan Zeitz, Louis, Associate Professor of Developmental Therapy & Clinical Investigation. A.B. 1948, Univer- sity of California; Ph.D. 1962, Stanford University Register 39 Degree Recipients 1982-83 Doctors of Philosophy Baetge, E. Edward, B.A. 1978, University of California at San Diego. Major: Neurobiology and Behavior. Fort Monmouth, New Jersey Burke, James A., B.A. 1975, Gettysburg College; M.S. 1977, Adelphi University. Major: Pharmacology. Garden City, New York Danska, Jayne S., B.A. 1977, Kenyon College. Major: Genetics. Roslyn Heights, New York Gardell, Stephen J., B.S. 1977, Boston College. Major: Biochemistry, Stamford, Connecticut Ghajar, Jamshid, B.A. 1973, M.A. 1975, University of California at Los Angeles. Major: Neurobiology and Behavior. Los Angeles, California Grassl, Steven M., B.S. 1974, Dickinson College; M.S. 1979, Rutgers University. Major: Physiology. East Lansing, Michigan Herz, Ruth E., B.S. 1959, Brooklyn College. Major: Biochemistry. New York, New York Kozak, Elena M., B.S. 1976, Jacksonville University. Major: Biochemistry. Jacksonville, Florida Kozak, Robert W., B.S. 1975, Eckerd College. Major: Microbiology. New York, New York Li, Yen, B.Sc. 1970, National Taiwan Normal Univer- sity; M.S. 1975, State University of New York. Major: Biochemistry. Taipei, Taiwan Ling, Geoffrey S. F, B.A. 1977, Washington University. Major: Pharmacology. Flemington, New Jersey Newcomb, Elizabeth W., B.S. 1966, University of Mas- sachusetts-Amherst; M.S. 1971, Kansas State University. Major: Genetics. New York, New York Ross, Christopher A., A.B. 1974, Princeton University. Major: Neurobiology and Behavior. New York, New York Ross, M. Elizabeth, 1975, State University of New York at Binghamton; M.D. 1980, Cornell University. Major: Neurobiology and 3ehavior. Cincinnati, Ohio Shin, Hee-Sup, M.M.S. 1977, M.D. 1974, Seoul Na- tional University. Major: Immunology. Seoul, Korea Sprouse, Jeffrey S., B.A. 1975, University of Delaware; M.S. 1977, Pennsylvania State University. Major: Pharmacology. Wilmington, Delaware Students 1983-84 Candidates for the Degree of Doctor of Philosophy Acosta, Alberto M., B.A. 1978, Columbia University. Major: Pathology. Havana, Cuba Albert, Vivian Risa, B.A. 1979, M.S. 1980, Stanford University. Major: Neurobiology and Behavior. Los Angeles, California Anderson, Mary E., B.A. 1977, Hollins College. Major: Biochemistry. San Antonio, Texas Arnold, Angelo N.. B.S. 1972, State University of New York at Stony Brook; M.S. 1978, C.W. Post. Major: Biochemistry. Brooklyn, New York Askari, Frederick K., B.A. 1981, Cornell University. Ma- jor: Pharmacology. Toledo, Ohio Batter, David K., B.S. 1979, University of Connecticut. Major: Neurobiology and behavior. New Haven, Connecticut Bauchwitz, Robert P., B.A. 1982, Harvard University. Major: Molecular Biology and Virology. Wilmington, Delaware Beaton, Ann R., B.S. 1976, Cornell University. Major: Molecular Biology and Virology Port Chester, New York Belkowski, Linda S., B.A. 1979, Rutgers University. Major: Molecular Biology and Virology. Perth Ann- boy, New Jersey Bergold, Peter J., B.S. 1977, Trinity College. Major: Molecular Biology and Virology. Teaneck, New Jersey Blank, Seymour G., B.E.E. 1965, City University of New York; M.E.E. 1968, New York University. Major: Physiology and Biophysics. Brooklyn, New York Braam, Janet, B.S., 1980, Southern Illinois. Major: Molecular Biology and Virology. Chicago, Illinois Brennan, Lynn A., B.A. 1974, Rutgers University. Ma- jor: Molecular Biology and Virology. New York, New York Bridges, Richard J., A.S. 1975, Santa Rosa Junior College; B.S. 1977, University of California at Davis. Major: Biochemistry. Santa Rosa, California Brodeur, David, B.S. 1979, College of William and Mary. Major: Molecular Biology and Virology. Brooklyn, New York Burns, Jacqueline P., B.S. 1978, Marymount Manhat- tan College. Major: Cell Biology and Genetics. New York, New York Chan, Marion Man-Ying, B.S. 1975, M.S. 1978, Univer- sity of Maryland. Major: Immunobiology. Hong Kong Chaum, Edward, B.A. 1979, Johns Hopkins University. Major: Genetics. Los Angeles, California Chen, Chun-Chang, B.S. 1977, Taiwan University, iv.a- jor: Biochemistry. Taipei, Taiwan Chen, Yao-Tseng, B.Med., 1981, College of Medicine, National Taiwan University. Major: Immunobiology. Tainan, Taiwan Cheung, Margaret K., B.S. 1978, University of Michi- gan. Major: Immunobiology. Hong Kong Chorney, Michael J., B.S. 1975, M.S. 1977, Lehigh University. Major: Genetics. Allentown, Pennsylvania Choy, Janet Wing, A.B. 1977, Smith College. Major: Biological Structure and Cell Biology. Wayne. New Jersey Clurman, Bruce E., B.A. 1981, University of Virginia. Major: Molecular Biology and Virology. Cherry Hill, New Jersey Colacino, Joseph M., B.A. 1975, University of Con- necticut; M.S. 1979, Southern Connecticut State College. Major: Immunobiology. New Haven, Connecticut Colmenares, Clemencia, B.S. 1976, Yale University. Major: Immunobiology. Bogota, Colombia Conti, Peter S., B.A. 1978, Johns Hopkins University. Major: Developmental Therapy and Clinical Inves- tigation. Yonkers, New York Cordon-Cardo, Carlos B., M.D. 1980, Autonomous University (Spain). Major: Pathology. Calella. Spain Davatelis, George N., B.A. 1977, Montclair State Col- lege; M.S. 1979, University of Hawaii. Major: Genetics. Paterson, New Jersey Davide, Joseph P., B.S. 1976. Manhattan College: M.S. 1982, New York Medical College Major: Bio- chemistry. Port Chester. New York Devaney. Margaret, B.S., B.A. 1977. University of Pennsylvania. Major: Microbiology. Lancaster, Pennsylvania DiPaola. Eugene A., B.S. 1974. Manhattan College Major: Genetics Boston. Massachusetts 40 Register Dorato, Andrea L, B.Sc, 1982, McGill University. Ma- jor: Molecular Biology and Virology Montreal, Quebec, Canada Doucette, Lynn Anne, B.Sc. 1981, McMaster Univer- sity (Canada). Major: Genetics. Toronto, Canada Drozdoff, Vladimir V, B.A. 1979, Bowdoin College. Major: Developmental Therapy and Clinical Inves- tigation. Cooper, Maine Eibl, Beatrice S., M.S. 1982, University of Vienna. Major: Biochemistry. Vienna, Austria Einheber, Steven, B.S. 1981, George Washington Uni- versity. Major: Cell and Developmental Biology. Washington, D.C. Febbraio, Maria, B.S. 1982, Fordham University. Ma- jor: Microbiology. Staten Island, New York Fitzpatrick, Susan M., B.S. 1978, St. John's University. Major: Biochemistry. Brooklyn, New York Garrisi, Garland J., B.A. 1977, Colgate University; M.S. 1979, Boston College. Major: Cell Biology and Genetics. Detroit, Michigan Giugliano, Edmund, B.S. 1978, Cornell University; M.S. 1982, C.W. Post College/Long Island Univer- sity. Major: Microbiology. Elmont, New York Gudewill, Ellen V, B.S. 1979, State University of New York at Stony Brook. Major: Pathology. Babylon, New York Green, William Nathan, B.Sc. 1978, University of Toronto. Major: Physiology and Biophysics. Buffalo, New York Groden, Joanna L, B.A. 1978, Middlebury College. Major: Genetics. Cambridge, Massachusetts Gulati, Poonam, B.A. 1982, Cornell University Major: Microbiology. Collins, New York Gummere, Gregory R., B.A. 1979, M.S. 1981, Univer- sity of Cincinnati. Major: Cell Biology and Genetics. Cincinnati, Ohio Hachfeld, Ughetta del Balzo, B.A. 1981, Barnard Col- lege. Major: Physiology and Biophysics. Rome, Italy Hariri, Robert, B.A. 1980, Columbia College. Major: Pathology. Forest Hills, New York *Harris, John M., B.S. 1980, University of California. Major: Pharmacology. La Grange, Illinois Harris, Paul E., A.B. 1978, University of California. Major: Cell Biology and Genetics. Philadelphia, Pennsylvania Haspel, Howard C, B.S. 1978, Polytechnic Institute of New York. Major: Cell Biology and Genetics. Brooklyn, New York Hinman, Lois M., B.S. 1969, Simmons College. Major: Biochemistry. New Haven, Connecticut Hodes, Marquis Z , A.B. 1973, Indiana University at Bloomington; M.S. 1976, Indiana University at In- dianapolis. Major: Immunobiology. Indianapolis, Indiana Hughes, Miranda J., B.S. 1978, State University of New York. Major: Pharmacology. Sydney, Australia Hwang, Onyou, A.B. 1982, Smith College. Major: Bio- chemistry. Seoul, Korea Ippolito, Catherine L, B.S. 1982, State University of New York at Stony Brook. Major: Biochemistry. East Meadow, New York Ishizaka, Sally T, B.A. 1976, Wellesley College. Ma- jor: Immunobiology Philadelphia, Pennsylvania Jaudon, Carol E., B.S. 1981. Mississippi University for Women Major: Molecular Biology and Virology Arlington, Texas 'Leave of absence Jeong, Gajin, B.S. 1976, M.S. 1978, Seoul National University. Major: Cell Biology and Genetics. Daejeon, Korea John, Ivan Boris, B.S. 1981, City University of New York. Major: Microbiology. Trinidad Kaseman, Deborah S., B.S. 1978, North Dakota State University. Major: Biochemistry. Ashley, North Dakota Kelly, Catherine D., B.A. 1981, State University of New York at Purchase. Major: Microbiology, Rockville Center, New York Klein, Deborah, B.A. 1973, New York University; M.S. 1978, Fordham University. Major: Genetics. Tea- neck, New Jersey Klein, Renate F, B.A. 1977, New York University. Ma- jor: Pathology. Munich, West Germany Lader, Eric Scott, B.S. 1981, Brooklyn College. Major: Genetics. Brooklyn, New York Lee, William T. L, B.A. 1978, Johns Hopkins Univer- sity Major: Genetics. Charlotte, North Carolina Lederman, Lynne, B.S. 1971, State University of New York at Stony Brook; M.S. 1974, Cornell University. Major: Molecular Biology and Virology. New York, New York Le Strange, Renee, B.A. 1978, University of North Carolina. Major: Immunobiology. Long Branch, New Jersey Levene, Richard B., B.S. 1972, Tulane University; M A. 1980, State University of New York. Major: Physiol- ogy. New York, New York Levine, Sulamita, M.D. 1975, M.S. 1980, University of Zulia Medical School (Venezuela). Major: Neu- robiology and Behavior. Maracaibo, Venezuela Li, Lucy Tung-Ching, B.S. 1973, Cornell University; M.S. 1979, New York University. Major: Molecular Biology and Virology. New York, New York Li, Luyuan, Graduate Certificate 1982, Sichuan Uni- versity. Major: Biochemistry. Zunyi City, People's Republic of China Lipkowitz, Stanley, B.A. 1977, Cornell University. Ma- jor: Biochemistry. Ferndale, New York Lockhart, Stephen Harold, A.B. 1977, Washington Uni- versity; M. Phil. 1979, Oxford University (England). Major: Developmental Therapy and Clinical Inves- tigation. St. Louis, Missouri Louie, Elaine, B.S. 1974, Brooklyn College. Major: Genetics. New York, New York Lufkin, Thomas C, A.B. 1981, University of California, Berkeley. Major: Molecular Biology and Virology. Birmingham, Michigan Martinez, Humberto Jose, M.D. 1975, University of Zulia Medical School (Venezuela). Major: Neu- robiology and Behavior. Maracaibo, Venezuela Matyas, John R., A.B. 1978, Cornell University. Major: Cell and Developmental Biology. Pittsburgh, Pennsylvania Maurer, David H., A.B. 1977, Cornell University. Major: Immunobiology. Newburgh, New York 'McGrath, John P., B.S. 1977, University of Scranton. Major: Biochemistry. Scranton, Pennsylvania Michitsch, Richard W., B.A. 1975, M.S. 1978, New York University. Major: Molecular Biology and Virol- ogy. Brooklyn, New York Mirenda, Carol A , B.A. 1979, Rutgers University. Ma- jor: Molecular Biology and Virology. Englewood, New Jersey Mitchell. Corinne A., B.S. 1981, Marymount College. Major: Genetics. Poughkeepsie, New York Register 41 Mok, Minsen, B.A. 1982, Johns Hopkins University. Major: Cell Biology and Genetics. Convent Station, New Jersey Montgomery, Kate T, B.A. 1978, Vassar College. Ma- jor: Molecular Biology and Virology. Chappaqua, New York Musket, David Brian, B.A. 1980, Boston College. Ma- jor: Neurobiology and Behavior. Providence, Rhode Island Mynarcik, Dennis C, B.S. 1978, University of Texas at San Antonio. Major: Biochemistry. San Antonio, Texas Nakamura, Dean H., B.S. 1974, M.S. 1977, University of Hawaii. Major: Genetics. Honolulu, Hawaii Nash, Barbara T, B.S. 1972, City University of New York; M.S. 1974, Yale University. Major: Biochemis- try. Larchmont, New York Nichols, Margaret E, A.I.M.L.S. 1962, Sir John Cass College (England); F.I.M.L.S. 1964, Mid Essex Col- lege (England). Major: Genetics. England Owen, Deborah G., B.S. 1974, University of Louisville. Major: Microbiology. Louisville, Kentucky Pearse, Roger N., B.A. 1977, Dartmouth College. Major: Pathology. Newport, Rhode Island Peterson, Christine, B.S. 1976, Herbert H. Lehman College; M.A. 1978, University of California, Santa Barbara. Major: Neurobiology and Behavior. Bronx, New York Powell, Andrea M., B.A. 1978, Manhattanville College. Major: Pharmacology. New Rochelle, New York Reinach, Fernando de C, B.S. 1978, M.S. 1980, Uni- versity of Sao Paulo, Brazil. Major: Cell and Developmental Biology. Brooklyn, New York Rico-Hesse, Rebecca, B.S. 1978, University of Nebraska; M.P.k 1980, University of Minnesota. Major: Microbiology. Los Angeles, California •Riley, Richard J., B.S. 1972, Manhattan College; M.S. 1976, New York University. Major: Developmental Therapy and Clinical Investigation. Yonkers, New York Robertson, Donna A., B.S. 1979, Syracuse University. Major: Pharmacology. White Plains, New York Rokovich, Joseph A., B.S. 1976, M.S. 1978, California State College. Major: Pathology. New Eagle, Pennsylvania Rosenberg, Charles D., A.B. 1978, Washington Uni- versity; M.S. 1979, State University of New York at Buffalo. Major: Pathology. Merrick, New York Rosenberg, Elizabeth A., B.A. 1981, Wesleyan Univer- sity. Major: Biochemistry. New York, New York Roux, Linda M., S B. 1978, Massachusetts Institute of Technology. Major: Immunobiology. Los Angeles, California Rubino, Heidi M., B.S. 1980, Muhlenberg College. Major: Biochemistry. New York, New York Rubino, Stephen D. B.S. 1980, Muhlenberg College. Major: Microbiology. Harrison, New York Rubock, Melissa J , B.A. 1982, University of Pennsyl- vania. Major: Molecular Biology and Virology. Levittown, New York Ruether, James E., B.A. 1981, University of Colorado. Major: Molecular Biology and Virology. Albany, New York Sadlik, John R., B.S. 1973, St. John's University. Major: Immunobiology. New York. New York Scotto, Kathleen V, B.S. 1977, St. John's University. Major: Molecular Biology and Virology. Queens. New York Shaffer, Rose Mary, B.S. 1980, Loyola College Major: Microbiology. Baltimore, Maryland Shaprio, Geoffrey I., B.A. 1981, Columbia University. Major: Molecular Biology and Virology. Schenec- tady, New York Signorelli, Kathy L, B.A. 1982, Wellesley College. Ma- jor: Molecular Biology and Virology. Strongsville, Ohio Sordillo, Emilia M., A.B. 1976, Harvard University; M.D. 1980, Cornell University. Major: Immunobiol- ogy. New York, New York Spiegel, Mary K., B.S. 1978, Duke University. Major: Pharmacology. Knoxville, Tennessee Stinavage, Paul Stanley, A A S. 1977, State University of New York at Morrisville; B.S. 1981, Marywood College. Major: Microbiology. Susquehanna, Pennsylvania Storella, Robert J., B.A. 1978, Wesleyan University. Major: Pharmacology. Brighton, Massachusetts Stuckey, Jeffrey A., B.S. 1977, Butler University. Major: Neurobiology and Behavior. Lima, Ohio Swiecicki, Alexandra, B.S. 1978, Cornell University. Major: Microbiology. Pittsburgh, Pennsylvania Taylor, Colleen, B.S. 1980, Siena College. Major: Mi- crobiology. Newark, New Jersey Teumer, Jeffrey K., B.A. 1979, Colgate University. Ma- jor: Molecular Biology and Virology. Sheboygan, Wisconsin Todd, G. Peter, B.S. 1977, Utah State University. Ma- jor: Biochemistry. Washington, D.C. Underwood, Mark, B.A. 1981, University of Vermont. Major: Neurobiology and Behavior. St. Albans, Vermont Verzosa, Purificacion O., B.S.M.T. 1969, Centro Esco- lar University; M.S. 1977, Fairleigh Dickinson University. Major: Microbiology. Monsey, New York Vigar, Diane C, B.S. 1976, M.S. 1981, Wagner Col- lege. Major: Microbiology. Staten Island, New York Wallace, David, B.S. 1966, City University of New York. Major: Microbiology. New York, New York Weisman, Steven M., B.S., B.A. 1981, Fairleigh Dickin- son University. Major: Pharmacology. Kansas City, Missouri Weissman, Lauren C, B.S. 1982. State University of New York at Binghamton. Major: Biochemistry. Binghamton, New York Yan, Ning, Diploma 1980, Nanjing University Major: Biochemistry. Nanjing, People's Republic of China Yang, Jung-Mou, M B. 1979, National Defense Medi- cal Center. Major: Physiology and Biophysics Taipei, Taiwan, Republic of China Zweis, Richard S., B.S. 1978, Syracuse University. Major: Pharmacology. Elmhurst, New York Candidate for the Degree of Master of Science Mohamed. Anwar Noori, M B.. Ch.B. 1977. Mosul Medical College. Major: Genetics. Mosul, Iraq Entering Students, 1983 Abate, Cormne, B.A. 1983, Fordham University Major: Neurobiology and Behavior. Brooklyn, New York Arnold. James B , B.A. 1982, Columbia College Ma- jor: Neurobiology and Behavior New York, New York Berger, Scott B.. B.A. 1983, Emory University Major: Neurobiology and Behavior Pittsburgh, Pennsylvania 42 Register Brock, Alice M., A.B. 1978, Smith College; M.S.H.S. 1980, Northeastern University. Major: Cell and De- velopmental Biology. Scarsdale, New York Buck, Charles R., B.S. 1983, College of Idaho. Major: Cell and Developmental Biology. Caldwell, Idaho Cruz-Bracho, Maria R., Licenciada en Quimica 1978, Simon Bolivar University; M.Sc. 1981, Instituto Ve- nezolano de Investigaciones Cientificas. (Venezuela) Major: Cell and Developmental Biol- ogy. Caracas, Venezuela. DiSanto, James R, B.A. 1983, Johns Hopkins Univer- sity. Sloan-Kettering Division. Cherry Hill, New Jersey Dogramajian, Mary Ellen, B.S. 1977, M.S. 1983, St. John's University. Major: Pharmacology. Huntington, New York Foxman, Brett, B.A. 1982, Boston University; M.D. 1982, Boston University School of Medicine. Penn Valley, Pennsylvania Harning, Ronald, B.A. 1975, Queens College of the City University of New York; M.A. 1977, New York University; M.S. 1983, Adelphi University. Major: Cell and Developmental Biology. Middle Village, New York Harris, Andrea, B.A. 1979, Boston University. Major: Microbiology. Hampton Bays, New York Heinrich, N. Julia, B.A. 1977, Brown University. Sloan- Kettering Division. New York, New York Hume, Clifford R., B.A. 1983, Carleton College. Sloan- Kettering Division. Incline Village, Nevada Jenkins, Deborah L, B.A. 1983, Williams College. Ma- jor: Biochemistry. Amherst, Massachusetts Kanter, Madge R., B.A. 1982, University of California at Santa Cruz. Sloan-Kettering Division. Palo Alto, California Kenny, Mark K., B.A. 1983, Wesleyan University. Sloan-Kettering Division. Chappaqua, New York Kornack, David R., B.S. 1983, Northern Illinois Univer- sity. Major: Neurobiology and Behavior. Lombard, Illinois Muller, Laurie, B.A. 1983, Barnard College. Major: Pharmacology. New York. New York Nocka, Karl H., B.A. 1983, Bowdoin College. Sloan- Kettering Division. Ridgewood, New Jersey Park, Dongeun, B.S. 1977, Seoul National University. Major: Neurobiology and Behavior. Bucheon, Korea Potter, Virginia P., S.B. 1977, M.S. 1978, Mas- sachusetts Institute of Technology; M.D. 1983, University of Chieti Medical School (Italy). Major: Pharmacology. New York, New York Russell, David S., B.A. 1982, Oberlin College. Sloan- Kettering Division. Chagrin Falls, Ohio Sehgal, Amita, B.Sc. 1981, Delhi University (India); M.Sc. 1983, Jawaharlal Nehru University School of Life Sciences (India). Major: Genetics. New Delhi, India Sikand, Gurleen S., B.Sc. 1978, M.Sc. 1982, Univer- sity of Manitoba (Canada). Major: Neurobiology and Behavior. Springfield, New Jersey Strauss, Donna L, B.S. 1980, State University of New York at New Paltz. Major: Pathology. Yonkers, New York Thormodsson, Finnbogi R., B.Sc. 1980, University of Iceland. Major: Neurobiology and Behavior. Reyk- javik, Iceland Till, Martha L, B.S. 1975, Colorado State University. Major: Microbiology. Chicago, Illinois von Kreuter, Betsy F, B.S. 1982, University of Ver- mont. Major: Pathology. Darien, Connecticut Wu, Kai-Yuan, B.A. 1983, New York University. Sloan- Kettering Division. Caldwell, New Jersey (People's Republic of China) Announcements Following is a list of Announcements published by Cornell University to provide information on graduate programs, faculty, facilities, curricula, and courses of various academic units. Announcement of: The Graduate School of Business and Public Administration Graduate Study in Engineering and Applied Science The Graduate School Graduate Study at the School of Industrial and Labor Relations The Law School The Medical College (New York City) The Graduate School of Medical Sciences (New York City) The New York State College of Veterinary Medicine In addition to the graduate Announcements listed above, the University publishes a master course catalog, Courses of Study, and a handbook for students, Introducing Cornell, which contain pertinent information about all aspects and academic units of the University. Requests for the publications listed above should be addressed to: Cornell University Announcements Building 7, Research Park Ithaca. New York 14850 (The writer should include a zip code.) Index 43 Cornell University Index Announcements, University, 42 Applications, 6 Biochemistry, 13 Interdivisional course, 30 Biophysics, see Developmental Therapy and Clinical Investigation, and see Physiology and Biophysics Calendar, 2 Cell and Developmental Biology, 14 Cell Biology and Genetics, 24 Courses, 14 Medical College Division, 14 Sloan-Kettering Division, 23 Degree recipients 1982-83, 39 Degree requirements, 7 Developmental Therapy and Clinical Investigation, 25 Examinations, 9 Admission to Candidacy Examination, 9 Final Examination, 9 Executive Committee, 6 Faculty Advisory Committee, 6 Faculty roster, 32 Financial assistance, 10 Foreign language requirements, 9 Genetics, 16, see also Cell Biology and Genetics Grades, 8 Health services, 11 Housing, see Residence halls Immunobiology, 27 In absentia, 8 Fee, 9 Leave of absence, 9 Fee, 9 Major and Minor Fields, 7 M.D.-Ph.D. program, 31 Medical College Division, 13 Courses, 14 Facilities, 5 Medical Scientist Training Program, 30 Microbiology, 17 Molecualr Biology and Virology, 29 Neurobiology and Behavior, 19 Pathology, 20 Pharmacology, 21 Ph.D.-M.D. program, 30 Physiology and Biophysics, 22 Prizes, 11 Provisional candidacy, 7 Registration, 8 Residence and residence units, 8 Residence halls, 11 Scholarships and awards, 10 Sloan-Kettering Division, 23 Courses, 23 Facilities, 5 Special Committee, 7 Special programs, 30 M.D.-Ph.D., 31 Ph.D.-M.D., 30 Special Students, 7 Student roster, 39 Summer research, 8 Tuition and fees, 9 Virology, see Molecular Biology and Virology Cornell University Medical College 1. Stavros S. Niarchos Medical Reseach Building A. The William Randolph Hearst Microbiology Research Building 2. William Hale Harkness Medical Research Building 3. Samuel J. Wood Library and Research Building 4. Biochemistry Pharmacology Building 5. Olin Hall Admissions Office 6. Livingston Farrand Apartments 7. Kips Bay Building 8. Lasdon House 9. "S" Building 1-.